L2HGDH - Wikipedia
L2HGDH codes for a protein that is 50 kDa in size. The L2HGDH protein contains a mitochondrial-targeting transit peptide [ 7 ] and is localized to the mitochondrial inner …
L2HGDH Gene - GeneCards | L2HDH Protein | L2HDH Antibody
2024年12月25日 · L2HGDH (L-2-Hydroxyglutarate Dehydrogenase) is a Protein Coding gene. Diseases associated with L2HGDH include L-2-Hydroxyglutaric Aciduria and D-2 …
Structure and biochemical characterization of l-2-hydroxyglutarate ...
l-2-hydroxyglutarate dehydrogenase (L2HGDH) is a mitochondrial membrane-associated metabolic enzyme, which catalyzes the oxidation of l-2-hydroxyglutarate (l-2-HG) to 2 …
心血管顶刊Circulation Research丨L-2-羟基戊二酸通过代谢重塑防 …
We examined the cardioprotective effects of L2HG accumulation against LFI and ischemia-reperfusion injury and its underlying mechanism using genetic mouse models. METHODS …
张进/胡泽平课题组Nature Metabolism合作发文揭示小鼠着床前胚 …
2021年10月20日 · 该文章系统描绘了小鼠着床前胚胎发育过程中的代谢重塑过程，发现关键代谢物L-2-羟基戊二酸（L-2-hydroxyglutarate, L-2-HG）通过影响表观遗传修饰参与调节早期胚胎发育 …
L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with …
2017年3月31日 · l-2-Hydroxyglutarate aciduria (L-2-HGA) is an autosomal recessive neurometabolic disorder caused by a mutation in the l-2-hydroxyglutarate dehydrogenase …
L2HGDH gene - MedlinePlus
Researchers have identified more than 70 mutations in the gene that cause a type of 2-hydroxyglutaric aciduria known as L-2-hydroxyglutaric aciduria (L-2-HGA). This condition has …
L2HGDH L-2-hydroxyglutarate dehydrogenase [ (human)]
2025年2月8日 · Gene ID: 79944, updated on 8-Feb-2025. This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2 …
L-2-羟基戊二酸脱氢酶（L2HGDH）基因 | MCE - MCE-生物活性 ...
该基因编码 L-2-羟基戊二酸脱氢酶，这是一种 FAD 依赖性酶，可在多种哺乳动物组织中将 L-2-羟基戊二酸氧化为 α-酮戊二酸。 该基因的突变会导致 L-2-羟基戊二酸尿症，这是一种罕见的常 …
MYC Regulation of D2HGDH and L2HGDH Influences the …
2020年5月21日 · Mitochondrial D2HGDH and L2HGDH catalyze the oxidation of D-2-HG and L-2-HG, respectively, into αKG. This contributes to cellular homeostasis in part by modulating the …