
慢性淋巴细胞白血病 - 维基百科,自由的百科全书
慢性淋巴细胞性白血病 (英語: Chronic lymphocytic leukemia,簡稱 CLL) ,這是一種最常見的 白血病 [1] 主要影響 B細胞。 B細胞來自於 骨髓,在 淋巴結 中發育,它主要的功能是產生 抗體。 在CLL中,B細胞的成長不受控制並且會堆積在骨髓和血液中使屬於正常紅血球細胞的空間被佔據。 CLL較常出現在年長者身上 [2] 在一些較少的案例中它在青年以及孩子身上出現過,這些案例中可能與遺傳相關。 男性相較女性更為容易出現CLL,在2014年UK的調查中產生CLL的新案例 …
Chronic Lymphocytic Leukemia: 2025 Update on the …
2025年1月28日 · Disease overview: Chronic lymphocytic leukemia (CLL) is the most frequent type of leukemia. It typically occurs in older patients and has a highly variable clinical course. Leukemic transformation is initiated by specific genomic alterations that interfere with the regulation of proliferation and apoptosis in clonal B-cells.
收藏贴 | 史上最全急性白血病知识 - 知乎 - 知乎专栏
急性白血病是造血干细胞的克隆性恶性疾病,发病时骨髓中异常的原始细胞(白血病细胞)大量增殖并浸润各种器官、组织,正常造血受抑制。 主要表现为肝脾和淋巴结肿大、贫血、出血及继发感染等。 (1)贫血往往是首起表现,呈进行性发展,主要由于正常RBC生成减少。 (2)发热可低热,亦可高达39~40℃以上,伴有畏寒、出汗等。 较高发热往往提示有继发感染。 感染可发生在各个部位,口腔炎、牙龈炎、咽峡炎最常见,可发生溃疡或坏死;肺部感染、肛周炎、肛旁脓 …
Chronic Lymphocytic Leukemia - StatPearls - NCBI Bookshelf
2023年3月7日 · Chronic lymphocytic leukemia is a chronic lymphoproliferative disorder characterized by monoclonal B cell proliferation. It is the most common adult leukemia in Western populations and comprises 25 to 30 percent of leukemias in the United States.
Acute lymphoblastic leukaemia of the L3 subtype in adults in the ...
Aim: Acute lymphoblastic leukaemia (ALL) with an L3 morphological FAB type is regarded by some as being synonymous with B cell ALL or ALL with a Burkitt-type chromosomal translocation—t (8;14), t (2;8), t (8;22). This paper describes a series from a population based study of 24 patients with L3 ALL presenting over 17 years.
Chronic lymphocytic leukemia - Symptoms and causes - Mayo Clinic
2024年12月20日 · Chronic lymphocytic leukemia (CLL) is a type of cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The term "chronic" in chronic lymphocytic leukemia comes from the fact that this leukemia typically progresses more slowly than other types of leukemia.
Chronic Lymphocytic Leukemia With Variant Genetics
2023年8月14日 · Chronic lymphocytic leukemia is a neoplasm of mature B cells almost always preceded by monoclonal B cell lymphocytosis (MBL) which refers to an absolute increase in peripheral blood lymphocytosis less than 5000/microL without any disease manifestations.
Chronic lymphocytic leukaemia: from genetics to treatment
2019年7月5日 · Chronic lymphocytic leukaemia (CLL), the most frequent type of leukaemia in adults, is a lymphoproliferative disorder that is characterized by the expansion of...
Chronic lymphocytic leukaemia: ESMO Clinical ... - Annals of …
2020年10月19日 · Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world with an incidence of 4.2/100 000/year. The incidence increases to more than 30/100 000/year at an age of >80 years. The median age at diagnosis is 72 years. About 10% of CLL patients are reported to be younger than 55 years.
Acute lymphoblastic leukaemia of the L3 subtype in adults in the ...
Aim: Acute lymphoblastic leukaemia (ALL) with an L3 morphological FAB type is regarded by some as being synonymous with B cell ALL or ALL with a Burkitt-type chromosomal translocation—t (8;14), t (2;8), t (8;22). This paper describes a series from a population based study of 24 patients with L3 ALL presenting over 17 years.