In cell biology, a lymphokine-activated killer cell (also known as a LAK cell) is a white blood cell, consisting mostly of natural killer, natural killer T, and T cells that has been stimulated to kill tumor cells, but because of the function in which they activate, and the cells they can successfully target, they are classified as different ...

应用CD3单抗诱导的杀伤细胞称为CD3抗体激活的杀伤细胞（CD3McAb activated killer cells,CD3AK），抗体含量在10-20ng/ml即可达到刺激杀伤活性的高峰，体外培养数天后即可出现明显的杀伤活性。 CD3AK激活需要 单核细胞 存在，其 增殖速度 和 细胞毒 活性均高于LAK。

Lymphokine-activated killer (LAK) cells are a unique subset of natural killer cells phenotypically induced by interleukin-2 (IL-2) to exhibit MHC restriction-independent cytotoxicity against tumor cells.

1986年12月17日 · Lymphokine-activated killer cells (LAK) are cytolytic lymphocytes with the unique capacity of killing NK-resistant fresh human tumor cells in short-term assays. LAK appear to kill autologous tumors as well as TNP-modified self and allogeneic tumors with complete crossreactivity, both at the populati …

Lymphokine activated killer (LAK) cells are a recently described cellular immune phenomenon with exciting potential for the treatment of tumours arising from solid organs. A comparison of some aspects of LAK cell precursors and LAK cell function was ...

2011年8月16日 · Clinical-grade LAKs/DCs represents a practical, effective combination cell immunotherapy for stimulation of both innate and adaptive anti-tumour immunity in cancer patients. Induction of...

2016年2月16日 · LAK, lymphokine-activated killer Cell, 即淋巴因子激活的杀伤细胞。 将外周血淋巴细胞在体外经淋巴因子白介素-2 (IL-2) 激活 3~5 天而扩增为具有广谱抗瘤作用的杀伤细胞。

LAK cell generation is similar in both methods of monocyte depletion; therefore, depletion of monocytes allows, LAK cell generation at high cell density. The PheOMe procedure provides an improved and convenient process for preparing LAK cells for adoptive immunotherapy.

LAK细胞即淋巴因子激活的杀伤细胞 (lymphokine active killer cell，LAK)，属于淋巴细胞的一种，由其前体细胞――裸细胞 (免疫细胞的一种)经过白细胞介素-2 (IL-2)孵育后发展而来。

LAK细胞疗法（lymphokine-activated killer cell therapy）是2007年全国科学技术名词审定委员会公布的免疫学名词，出自《免疫学名词》第一版。 一种抗肿瘤的生物治疗方法。 即采集、分离自体或同种异体淋巴细胞，体外应用IL-2等细胞因子对其进行激活和扩增，使之转化为具有杀瘤作用的效应细胞，再过继输入给患者。 一种抗肿瘤的生物治疗方法。 即采集、分离自体或同种异体 淋巴细胞，体外应用IL-2等 细胞因子 对其进行激活和扩增，使之转化为具有杀瘤作用的 效应细 …