LCLs are EBV-transformed lymphoblastoid B-cell lines, which can be easily established by EBV infection or derived spontaneously from peripheral blood B lymphocytes. From: Handbook of …

2017年3月8日 · Lymphoblastoid cell lines (LCLs) transformed by Epstein-Barr virus (EBV) serve as an unlimited resource of human genomic DNA. The protocol that is widely used to...

2021年5月25日 · Here, we extensively profiled a panel of human, chimpanzee, gorilla, orangutan, and macaque lymphoblastoid cell lines (LCLs), using ChIP-seq for five histone marks, ATAC …

Infection of human B cells with EBV in vitro results in their immortalization and the resulting cell lines are named lymphoblastoid cell lines (LCLs) (1). In these cells, EBV establishes mainly a …

Transformation of peripheral B lymphocytes by Epstein-Barr virus (EBV) is the method of choice for generating lymphoblastoid cell lines (LCLs). This method has been in use for the last two …

Lymphoblastoid cell lines (LCLs) can be generated easily by in vitro EBV infection of B lymphocytes collected from any individual. In vitro, these EBV-infected B cell cultures yield …

2011年11月8日 · Infection of B cells with Epstein-Barr virus (EBV) leads to proliferation and subsequent immortalization, resulting in establishment of lymphoblastoid cell lines (LCL) in …

2018年6月20日 · Lymphoblastoid cell lines (LCLs) have been by far the most prevalent cell type used to study the genetics underlying normal and disease-relevant human...

人类淋巴母细胞系(lcl)是一种永久生存的细胞系,可用于产生免疫球蛋白,mhc-抗原,干扰素和其它淋巴因子,也可与种内或种间细胞杂交成为杂交瘤细胞.因此,近年来lcl已广泛用于免疫学实验.lcl常 …

We report here that a very high frequency of human B cell-derived lymphoblastoid cell lines (LCL) constitutively produce MHCII + FasL + exosomes that can induce apoptosis in CD4 + T cells. …