pH-Activatable cell penetrating peptide dimers for potent …
2021年2月10日 · PTX-LH 2 complex shows strong antitumor effects in triple-negative breast cancer cells grafted mouse model. We developed a pH-activatable cell-penetrating peptide …
Pro-metastatic collagen lysyl hydroxylase dimer assemblies
2018年2月6日 · Here, we report a 2 Å crystal structure and X-ray scattering on dimer assemblies for the LH domain of L230 in Acanthamoeba polyphaga mimivirus. Loop residues in the double …
Molecular architecture of the multifunctional collagen lysyl ...
2018年8月8日 · Here, we present high resolution crystal structures of full-length human LH3 in complex with cofactors and donor substrates. The elongated homodimeric LH3 architecture …
Dimerization of human lysyl hydroxylase 3 (LH3) is mediated by …
2011年1月1日 · Lysyl hydroxylases (LH), which catalyze the post-translational modifications of lysines in collagen and collagen-like proteins, function as dimers. However, the amino acids …
A Helix Heterodimer in a Lipid Bilayer: Prediction of the Structure …
2011年10月10日 · Dimerization of transmembrane (TM) α helices of membrane receptors plays a key role in signaling. We show that molecular dynamics simulations yield models of integrin …
Expression of antimicrobial peptide LH multimers in
2009年5月1日 · Fusion LH dimer was expressed as inclusion body at a portion of 35% of total cell protein and could be well purified by Ni 2+ -chelating chromatography. The recombinant LH …
A dileucine determinant in the carboxyl terminal sequence of …
2011年6月6日 · Previously we demonstrated using secretogogue stimulated secretion and pulse chase kinetics that the LHβ carboxyl terminal heptapeptide plays a major role in the sorting of …
Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized ...
2018年2月6日 · Here, we report a 2 Å crystal structure and X-ray scattering on dimer assemblies for the LH domain of L230 in Acanthamoeba polyphaga mimivirus. Loop residues in the double …
Pro-metastatic collagen lysyl hydroxylase dimer assemblies
2018年2月6日 · Here, we report a 2 Å crystal structure and X-ray scattering on dimer assemblies for the LH domain of L230 in Acanthamoeba polyphaga mimivirus. Loop residues in the double …
Expression of antimicrobial peptide LH multimers in ... - PubMed
Fusion LH dimer was expressed as inclusion body at a portion of 35% of total cell protein and could be well purified by Ni (2+)-chelating chromatography. The recombinant LH was released …