同源异形基因 - 维基百科，自由的百科全书
同源异形基因（英語： Hox genes ）是生物體中一類專門調控生物形體的基因，一旦這些基因發生突變，就會使身體的一部分變形。 其作用機制，主要是調控其他有關於 細胞分裂 、 紡錘體 …
关于Hox genes：从果蝇说起 - 知乎 - 知乎专栏
homeobox genes的子集——HOX genes（只在动物中发现）复制后成为HOX clusters. HOX gene 突变后产生homeotic mutations，影响动物形态发育. 同源异型基因（英语：homeotic …
Role of HOXA9 in leukemia: dysregulation, cofactors and essential ...
HOXA9 is a homeodomain-containing transcription factor that plays an important role in hematopoietic stem cell expansion and is commonly deregulated in acute leukemias. A variety …
Hox genes in evolution: protein surfaces and paralog groups
1997年4月1日 · Classifying Hox genes in Caenorhabditis elegans The small Hox cluster in the nematode C. elegans consists of four genes. In 3' to 5" order, they are ceh-13, 1in-39, mab-5 …
Expression of Hox Genes in the Nervous System of Vertebrates
Studies on the patterns of expression, regulation and function of the vertebrate Hox gene family have played a key role in aiding our understanding of the basic ground plan of the CNS and …
Studies have also shown that HOX genes appear to be important for normal T lymphocyte and activated natural killer cell function. Overexpression of Hox-b4 in trans-planted murine marrow …
THE ROLE OF HOX PROTEINS IN LEUKEMOGENESIS; INSIGHTS …
Increased and sustained Hox expression is found in a subset of leukemia with chromosomal translocations involving the MLL gene. 1–3 This observation suggested that the MLL gene …
Biology of Hox Genes: Questions and Technological Challenges
2025年1月3日 · Hox genes are crucial in determining segmentation identity in developing embryos, which ultimately sets an anteroposterior body axis. Over a century of research has …
Hox基因及其进化机制的研究进展-【维普期刊官网】- 中文期刊服 …
Hox基因高度保守,通常成簇存在,编码一类转录因子,在个体胚胎发育中起着重要的调控作用。 近期研究表明,基因复制、基因序列变异及选择压力对Hox基因簇的产生和进化有重要作用,...
同源异形基因 - 维基百科，自由的百科全书
同源异形基因（英语： Hox genes ）是生物体中一类专门调控生物形体的基因，一旦这些基因发生突变，就会使身体的一部分变形。 其作用机制，主要是调控其他有关于 细胞分裂 、 纺锤体 …