
Liquid–liquid phase separation in human health and diseases
2021年8月2日 · Recent studies have revealed evidences that indicate that LLPS plays a vital role in human health and diseases. In this review, we describe our current understanding of LLPS …
Liquid-liquid phase separation in human diseases: Functions, …
2024年12月1日 · In this review, we introduce the insights and findings on the formation, regulation and function of LLPS. The role of LLPS in human diseases, including cancer, …
液-液相分离调节免疫细胞活化和关键信号传导的研究进展 - PMC
Liquid-liquid phase separation (LLPS) is a process in which certain proteins or protein-RNA complexes form phase-separated droplets with different components and properties through …
Liquid-liquid phase separation (LLPS) in cellular physiology and …
This review will summarize the principle and components of LLPS, and describe how LLPS regulate these numerous biological processes and disruption of LLPS would cause disease …
Liquid-liquid phase separation: Fundamental physical principles ...
2023年12月1日 · This review offers a concise overview of LLPS in soft matter, emphasizing its relevance in soft material engineering. We delve into fundamental mechanisms, focusing on …
The role of liquid-liquid phase separation in the disease …
2024年11月1日 · LLPS describes a phenomenon that different components in cells collide and fuse with each other to form droplets, so that some components are wrapped in droplets and …
Physiology and pharmacological targeting of phase separation
2024年1月20日 · Liquid–liquid phase separation (LLPS) in biology describes a process by which proteins form membraneless condensates within a cellular compartment when conditions are …
Liquid-liquid phase separation (LLPS) in cellular physiology and …
2021年8月15日 · Liquid-liquid phase separation (LLPS) has emerged as a mechanism that has been used to explain the formation of known organelles (e.g. nucleoli, promyelocytic leukemia …
Liquid-liquid phase separation in human health and diseases
2021年8月2日 · Emerging evidence suggests that liquid-liquid phase separation (LLPS) represents a vital and ubiquitous phenomenon underlying the formation of membraneless …
Role of liquid-liquid phase separation in cancer: Mechanisms and ...
2024年9月17日 · Here, we comprehensively summarize the multifaceted roles of LLPS in tumor biology from the perspective of cancer hallmarks, including genomic stability, metabolic …
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