Phosphatidylserine (PS) is a negatively charged molecule. The amount of the negative zeta potential in the liposomes depends on the molar percentage of the phosphatidylserine (PS) in the formulation. The matrix lipid, DOPC, that is used in the formulations does not significantly contribute to the charge of the liposomes.

Lyophilized liposomes product series are freeze-dried liposomes with various types of lipids and wide range of zeta potentials and different properties. These products should be used by scientists who understand liposome formulation and have the proper equipment to check the size, separate non-encapsulated drugs and do the proper assays.

Trehalose is used as a lyoprotectant in all freeze-dried liposome formulation. The size distribution after hydration of the freeze-dried formulation will be around 100 nm. Freeze-dried liposomes should be kept at -20°C. Lyophosome™ is a white lyophilized powder.

LPS-506. Copy Link. Email. Lyophilized Anionic Liposomes - Phosphatidylserine (PS)-based. DOPS:DOPC (40:60 molar ratio) Sign In to View Organizational & Contract Pricing. All Photos (1) UNSPSC Code: 12352211. Properties. form. lyophilized powder. composition. DOPS:DOPC (40:60 molar ratio) color. white to off-white.

LBP plays a role in the innate immune response. Alao,LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS.

Lipid Composition for LPS-506 Amount (mg/vial) Amount (umol) Molar Ratio Percentage; 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt) 4.07: 5.03: 40: 1,2-dioleoyl-sn-glycero-3-phosphocholine: 5.93: 7.54: 60: Total 10.00 mg/vial 12.57 umol 100; Lipid Composition for LPS-507 Amount (mg/vial) Amount (umol) Molar Ratio Percentage; 1,2 ...

Product Number : LPS-501, LPS-502, LPS-503, LPS-504, LPS-505, LPS-506, LPS-507, LPS-508, LPS-509, LPS-510, LPS-511, LPS-512, LPS-513 Brand : LYOPHOSOME™ Company Address : ENCAPSULA NANOSCIENCES LLC 5409 MARYLAND WAY, SUITE 360 BRENTWOOD, TN, 37027 Technical Phone : 615-884-4442 Fax : 615-250-8747 ...

It was found that miR-506 was upregulated following LPS treatment in DPSCs. The inhibition of miR-506 in LPS-treated DPSCs led to attenuated inflammation and deactivation of the TLR4 pathway. Furthermore, the bioinformatic analysis and dual-luciferase reporter gene assay indicated that miR-506 could target the 3′-UTR of sirtuin 1 (SIRT1).

2019年12月26日 · The inhibition of miR-506 in LPS-treated DPSCs led to attenuated inflammation and deactivation of the TLR4 pathway. Furthermore, the bioinformatic analysis and dual-luciferase reporter gene assay indicated that miR-506 could target the 3'-UTR of sirtuin 1 (SIRT1).

The results showed that CKD-506 pretreatment reduced the LPS-induced DNA binding of NF-κB in both COLO 205 (A) and RAW 264.7 cells (B). The positions of the NF-κB specific complex are indicated...