IL-10 mRNA expression was induced by LPS at 10-h, and was maximal at 16-h. IL-10 protein secretion was induced at 16-h and was maximal at 24-h. Our data reveal the temporal kinetics …

2020年5月26日 · Previous studies have shown that baicalin, an active ingredient of the Chinese traditional medicine Huangqin, attenuates LPS-induced inflammation by inhibiting the …

图1 检测p-p65使用的细胞模型比例. 刺激物. 使用的最多的刺激物为lps（脂多糖），lps是革兰氏阴性细菌细胞壁外壁的组成成分，通过tlr4来激活nfκb信号通路。

2021年2月3日 · The p-p65 can be up-regulated by LPS alone or co-culture with THP-1-derived macrophages, suggesting possible roles of proinflammatory cytokines on regulating Ang1 and …

2017年5月3日 · We tested the model proposed by Cheng et al. using real-time single cell analysis in macrophages expressing EGFP-tagged p65 and a TNFα promoter-driven mCherry. …

技术(chromatin immunoprecipitation assay, ChIP)验证NRF1的靶基因RELA (NF-κB p65编码基因)。结果显示：LPS处理组小鼠 肺组织或L132细胞NRF1表达水平明显上升，炎症因子p65及其 …

LPS-stimulated NF-κB p65 dynamic response marks the initiation of TNF expression and transition to IL-10 expression in RAW 264.7 macrophages. During injury and infection, …

2024年7月1日 · NF-κB p65 and TCF-4 binding in the nucleus was associated with LPS stimulation. Proinflammatory cytokine plays a central role in host defense and acute …

Direct binding of NF-κB p65 subunit to the promoter elements of select miRNA genes was confirmed by chromatin immunoprecipitation (ChIP) and promoter luciferase analysis. Thus, a …

Previous studies have shown that baicalin, an active ingredient of the Chinese traditional medicine Huangqin, attenuates LPS-induced inflammation by inhibiting the activation of TLR4/NF-κBp65 …