2022年10月1日 · In this study, we developed two LPS morphologies using LPS from Escherichia coli as a model to study the in vitro hydrolytic response when using a lipase treatment. The hydrolysis was performed using lipase b from Candida antarctica to understand the catalytic effect in removing fatty acids from its lipid A moiety on different LPS aggregates.

2017年8月29日 · Transport of lipopolysaccharides (LPS) to the surface of the outer membrane is essential for viability of Gram-negative bacteria. Periplasmic LptC and LptA proteins of the...

2025年2月13日 · The outer-membrane lipopolysaccharide (LPS, endotoxin) of gram-negative bacteria is highly immunostimulatory and induces severe pathology in humans. Investigation of natural and reconstituted membrane systems by small angle X-ray scattering (SAXS) revealed that the supramolecular organization and 3D structure of endotoxin molecules are major ...

2018年3月1日 · The native starch and their corresponding SNPs have been studied firstly with the LPS SAXS instrument (measurement range 0.02–0.3 Å −1). Study of native granules have shown that both the standard starch and waxy maize exhibit a lamellar peak whose position is located at q peak equals 0.07 and 0.09Å −1 , respectively ( Fig. 9 A and B).

2023年11月1日 · SAXS combined with wide-angle X-ray scattering (WAXS) experiments revealed significant changes in the layered arrangement of PSUR dispersions upon LPS incubation. The observing broad and unseparated peaks indicated a weaker correlation between sheets and the multilayer structure of PSUR expanded after longer incubation with LPS ( Fig. 9 C).

2023年3月27日 · Recently, lipopolysaccharides (LPSs) with low dispersity have been developed, and here, we examine the self-assembly of two such model systems in comparison with native polydisperse bacterial LPS. The recent COVID-19 pandemic has focused attention on vaccine adjuvants, which boost the immunogenic response of vaccines.

Transport of lipopolysaccharides (LPS) to the surface of the outer membrane is essential for viability of Gram-negative bacteria. Periplasmic LptC and LptA proteins of the...

2009年5月15日 · The O,N-deacylated derivative (deON) and polysaccharide part (PS) from the lipopolysaccharide (LPS) of Escherichia coli C strain were separated by strongly basic anion-exchange chromatography (SAX) based on the differences in the number of charged phosphate and ethanolamine substituents.

2020年7月10日 · Emergent nanoscale order in materials such as self-assembled lipid phases, colloidal materials and metal-organic frameworks is often characterized by small-angle X-ray scattering (SAXS)....

We evaluated the behaviour of a clinically used modified porcine pulmonary surfactant (PSUR) in the presence of LPS in a dynamic system mimicking the respiratory cycle. Polymyxin B (PxB), a...