Liver receptor homolog-1 - Wikipedia
The liver receptor homolog-1 (LRH-1) also known as totipotency pioneer factor NR5A2 (nuclear receptor subfamily 5, group A, member 2) is a protein that in humans is encoded by the …
胆汁酸受体及其作用途径 - 知乎 - 知乎专栏
LRH-1（Liver receptor homolog-1），肝受体同源物-1。 LRH-1是一种配体激活的转录因子，属于核受体蛋白家族。 激活CYP7A1表达的转录因子。 LRH-1 通常充当单体，并且在没有配体的 …
Liver receptor homolog-1: structures, related diseases, and drug ...
2024年4月17日 · Liver receptor homolog-1 (LRH-1), a member of the nuclear receptor superfamily, is a ligand-regulated transcription factor that plays crucial roles in...
药物发现│靶向LRH-1药物研发进展 - 知乎 - 知乎专栏
肝受体同源物-1 (LRH-1, NR5A2) 是一种配体激活的转录因子，属于核受体蛋白家族。 它也被称为 fushi tarazu因子1 （FTZ-F1）、甲胎蛋白转录因子（FTF）、胰腺同源受体1（PHR-1）、 …
Emerging functions of the nuclear receptor LRH-1 in liver …
2021年8月1日 · LRH-1 is a key regulator of bile acid, lipid, glucose and methyl group homeostasis. LRH-1 coordinates several cellular stress responses in the liver. LRH-1 is a …
Pharmacological LRH-1/Nr5a2 inhibition limits pro-inflammatory cytokine ...
2020年2月28日 · Liver receptor homolog-1 (LRH-1, Nr5a2) is an orphan nuclear receptor mainly expressed in tissues of endodermal origin, where its physiological role has been...
LRH-1: an orphan nuclear receptor involved in development, …
2004年5月1日 · The liver receptor homolog-1 (LRH-1; NR5A2) and steroidogenic factor-1 (SF-1; NR5A1) are two orphan members of the Ftz-F1 subfamily of nuclear receptors. LRH-1 is …
Liver receptor homolog-1: structures, related diseases, and drug ...
Liver receptor homolog-1 (LRH-1), a member of the nuclear receptor superfamily, is a ligand-regulated transcription factor that plays crucial roles in metabolism, development, and …
LRH-1: an orphan nuclear receptor involved in ... - ScienceDirect
2004年5月1日 · The metabolic pathways controlled by liver receptor homolog-1 (LRH-1). LRH-1 plays a key role in metabolism because several of its target genes are crucial to the regulation …
LRH-1: an orphan nuclear receptor involved in development
The liver receptor homolog-1 (LRH-1; NR5A2) and steroidogenic factor-1 (SF-1; NR5A1) are two orphan members of the Ftz-F1 subfamily of nuclear receptors. LRH-1 is expressed in tissues …