2025年1月3日 · Lymphangioleiomyomatosis (LAM) is a low-grade destructive metastasizing PEComatous tumor 1 resulting from the proliferation of LAM cells in the lung, kidney and axial lymphatics. The disease is caused by mutations of the TSC2 or TSC1 genes and is more commonly sporadic rather than inherited.

2021年8月31日 · A mnemonic to remember the diagnostic criteria of lymphangioleiomyomatosis (LAM) is: V: VEGF-D >800 pg/mL. ADVERTISEMENT: Supporters see fewer/no ads.

LAM – Lymphangioleiomyomatosis is a genetic disorder mostly in women (in a sporadic form) or in the context of tuberous sclerosis complex. Typically numerous small and round cysts in diffuse distribution, sometimes with pleural effusion (chylothorax). Patients can also present with renal angiomyolipomas.

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2005年5月1日 · LAM is characterized pathologically by abnormal proliferation of LAM cells in the lungs and in thoracic and retroperitoneal lymphatics. Thirty-three cases of LAM were reviewed retrospectively for clinical and radiologic findings.

2023年6月11日 · Lymphangioleiomyomatosis (LAM) is a primary disease of the lung parenchyma caused by abnormal growth of smooth muscle cells in the lung vasculature, lymphatics, and alveoli that leads to the formation of multiple cysts in the lungs bilaterally and respiratory symptoms, such as dyspnea on exertion.

2002年10月1日 · Lymphangioleiomyomatosis (LAM) is a rare disease characterized by pulmonary cysts at computed tomography (CT) and proliferation of abnormal smooth muscle cells at lung biopsy. Almost all patients are female, and all have pulmonary cysts at high-resolution CT.

Lymphangioleiomyomatosis (LAM) is an indolent, progressive growth of smooth muscle cells throughout the lungs, pulmonary blood vessels, lymphatics, and pleurae. It is rare and occurs in young women. Symptoms are dyspnea, cough, chest pain, and hemoptysis; spontaneous pneumothorax is common.

2023年12月10日 · Lymphangioleiomyomatosis (LAM) is a rare lung disease characterised by the abnormal proliferation of smooth muscle-like cells (LAM cells) in the lungs, lymphatic system, and kidneys. These abnormal cells invade the tissue of these organs, leading to the formation of cysts, nodules, and tumours.

2021年1月3日 · Lymphangioleiomyomatosis (LAM) is a rare idiopathic disease affecting women that was first described by von Stossel in 1937. LAM is characterized by nonneoplastic peribronchial,...