
LAMA5 Gene - GeneCards | LAMA5 Protein | LAMA5 Antibody
2024年12月25日 · LAMA5 (Laminin Subunit Alpha 5) is a Protein Coding gene. Diseases associated with LAMA5 include Nephrotic Syndrome, Type 26 and Bent Bone Dysplasia Syndrome 2 . Among its related pathways are Integrin Pathway and ERK Signaling .
Laminin, alpha 5 - Wikipedia
Laminin subunit alpha-5 is a protein that in humans is encoded by the LAMA5 gene. [5][6] Components of the extracellular matrix exert myriad effects on tissues throughout the body.
层粘连蛋白亚基α5(LAMA5)基因 | MCE - MCE-生物活性 ...
Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]
LAMA5 laminin subunit alpha 5 [ (human)] - National Center for ...
LAMA5 promotes human umbilical vein endothelial cells migration, proliferation, and angiogenesis and is decreased in preeclampsia. Maternal alloimmune IgG causes anti-glomerular basement membrane disease in perinatal transgenic mice that express human laminin alpha5.
Development:细胞外基质或能引导上皮细胞的生长和功能发挥!
2021年7月6日 · 这篇研究报告中,研究者发现,这些细胞在其周围会产生ECM蛋白,从而就会调节细胞外上皮细胞的生长和分化,名为Lama5蛋白的产生则能够加强这些 ...
LAMA5 laminin subunit alpha 5 [ Homo sapiens (human) ]
2024年10月28日 · Title: Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis. A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects.
LAMA5突变相关遗传病的基因型及临床表型分析
2024年12月9日 · 目的 探讨lama5基因变异致相关遗传疾病的临床特征和基因变异特点。 方法 通过Pubmed、Web of cience 等数据库,搜索目前全球范围内已报道的LAMA5突变病例,总结分析LAMA5基因变异所致相关遗传疾病的临床表型及基因测序结果。
肿瘤源性层粘连蛋白 α5 (LAMA5) 促进结直肠肝转移生长、分支血 …
该数据证明了肿瘤炎症诱导结直肠癌细胞中 LAMA5 表达的机制。 LAMA5 是肝转移瘤成功生长所必需的,它促进分支血管生成并调节 Notch 信号传导。 Hepatic metastatic growth is dependent upon stromal factors including the matrisomal proteins that make up the extracellular matrix (ECM). Laminins are ECM glycoproteins with several functions relevant to tumour progression including angiogenesis.
LAMA5人源基因|LAMA5基因突变_致病性_靶点-RDDC官网
Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Lama5 - laminin, alpha 5 基因 | MCE - MCE-生物活性分子大师
Acts upstream of or within several processes, including animal organ development; morphogenesis of an epithelium; and protein localization to plasma membrane. Located in basement membrane and neuromuscular junction. Part of …