
Long-term potentiation - Wikipedia
Long-term potentiation (LTP) is a persistent increase in synaptic strength following high-frequency stimulation of a chemical synapse. Studies of LTP are often carried out in slices of the …
Molecular Mechanisms of Early and Late LTP - PubMed
LTP is the most intensively studied cellular model of the memory and generally divided at least two distinct phases as early and late. E-LTP requires activation of CaMKII that initiates …
突触效能的长时程增强(LTP)和抑制(LTD) | 学习和记忆 - 知乎
2021年6月21日 · 我们回到LTP现象来,LTP现象可以被分为早期阶段Early-LTP(E-LTP)和后期阶段Late-LTP(L-LTP)。 在E-LTP阶段,所涉及的反应机制响应比较快速,没有新蛋白合成 …
突触可塑性 Synaptic Plasticity: LTP - 知乎 - 知乎专栏
利用4串或更多的刺激产生的LTP可以维持超过24小时,这被称为Late-LTP (L-LTP)。 L-LTP需要cAMP,PKA以及基因转录、新蛋白质的合称来实现。 具体通路如下图(蓝色箭头)。
学术前沿!南方医科大学高天明课题组首次发现调节突触可塑性和 …
2021年10月20日 · 海马脑区的 长时程增强( long-term potentiation ,LTP)是研究最多的一类突触可塑性,同时也被认为是学习记忆的一种细胞机制【1 】。 LTP根据其维持时间的长短可分 …
長期增強作用 - 维基百科,自由的百科全书
長期增強作用(英語: Long-term potentiation ,LTP)又稱长时程增强作用、長期增益效應,是由于同步刺激两个神经元而发生在两个神经元信号传输中的一种持久的增强现象。
Molecular Mechanisms of Early and Late LTP - Springer
2018年12月6日 · LTP is the most intensively studied cellular model of the memory and generally divided at least two distinct phases as early and late. E-LTP requires activation of CaMKII that …
Late-phase long-term potentiation: getting to the nucleus
Long-term potentiation (LTP) is defined as a long-lasting increase in the magnitude of the synaptic response of a neuron following a short train of high-frequency afferent...
BDNF mechanisms in late LTP formation: A synthesis and breakdown
Brain-derived neurotrophic factor (BDNF) has emerged as a regulator of stable, late phase long-term potentiation (L-LTP) at excitatory glutamatergic synapses in the adult brain. However, the …
The late maintenance of hippocampal LTP: requirements, …
Our review focuses on the mechanisms which enable the late maintenance of hippocampal long-term potentiation (LTP; >3h), a phenomenon which is thought to underlie prolonged memory. …
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