Lactate dehydrogenase A catalyzes the inter-conversion of pyruvate and L- lactate with concomitant inter-conversion of NADH and NAD +. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumors, and belongs to …

乳酸脱氢酶（lactate dehydrogenase，LD或LDH，EC1.1.1.27）是一类NAD依赖性激酶，有LDHA、LDHB、LDHC三种亚基，可构成6种四聚体同工酶。 动物乳酸脱氢酶是由4个亚单位组成的四聚体，常见的A、B两种亚基构成的5种LDH同工酶（LDH1-5），C亚基则仅组成一种LDH同工酶 …

乳酸脱氢酶 （英語： Lactate dehydrogenase； EC 1.1.1.27），縮寫： LDH 或 LD，是一个广泛存在于各种生物体中的酶，包括了植物与动物。 乳酸脱氢酶存在于四种不同的酶分类中。 其中两种是依赖 细胞色素c 的酶，它们各自作用于D-乳酸 （EC 1.1.2.4） 与L-乳酸 （EC 1.1.2.3）。 乳酸脱氢酶催化 丙酮酸 与 乳酸 之间的互变并伴随着还原型烟酰胺腺嘌呤二核苷酸与其氧化型之间互变。 此酶也可催化 2-羟基丁酸 的脱氢作用，但其为较乳酸劣势的底物。 注释：也氧化其 …

Our LDHA polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse, Goat and Sheep. These antibodies have been verified by Knockdown and Independent antibody to confirm specificity to LDHA. Find the LDHA antibody that fits your needs.

2024年12月25日 · LDHA (Lactate Dehydrogenase A) is a Protein Coding gene. Diseases associated with LDHA include Fanconi-Bickel Syndrome and Tango2-Related Metabolic Encephalopathy And Arrythmias. Among its related pathways are glycolysis (BioCyc) and Regulation of pyruvate metabolism.

该基因编码的蛋白质在无氧糖酵解的最后一步催化 L-乳酸和 NAD 转化为丙酮酸和 NADH。 该蛋白质主要存在于肌肉组织中，属于乳酸脱氢酶家族。 该基因的突变与劳力性肌红蛋白尿有关。 已发现该基因编码不同异构体的多个转录变体。 人类基因组包含该基因的几个非转录假基因。 [RefSeq 提供，2008 年 9 月] The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis.

The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the Lactate Dehydrogenase family. Mutations in this gene have been linked to hemolytic anemia and early postimplantation death in mice.

Lactate Dehydrogenase A (LDHA; LDH5), EC 1.1.1.27, is one of five isoforms of the lactate dehydrogenase family. It catalyzes the conversion of pyruvate to lactate under anaerobic conditions and is key in the altered glycolytic metabolism that is a feature of cancer cells.

2024年7月30日 · 乳酸脱氢酶 （lactate dehydrogenase，LDH）是一类 NAD 依赖性激酶， 是糖无氧酵解及糖异生的重要酶系之一，广泛分布于各种组织中，其中 以心肌、骨骼肌和肾脏含量最丰富，其次为肝脏、脾脏、胰腺、肺脏和肿瘤组织 。红细胞内LDH约为正常血清的100倍。LDH是 …

Acts upstream of or within response to hypoxia. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Is expressed in several structures, including cardiovascular system; gill; liver; muscle; and nervous system. Orthologous to human LDHA (lactate dehydrogenase A). None. Something went wrong fetching data.