LILRB2 Gene - GeneCards | LIRB2 Protein | LIRB2 Antibody
2024年12月25日 · LILRB2 (Leukocyte Immunoglobulin Like Receptor B2) is a Protein Coding gene. Diseases associated with LILRB2 include Malaria and Leukemia, Acute Myeloid. Among …
LILRB2 - Wikipedia
Leukocyte immunoglobulin-like receptor subfamily B member 2 is a protein that in humans is encoded by the LILRB2 gene. [ 3 ] [ 4 ] [ 5 ] This gene is a member of the leukocyte …
抗癌理想靶点新选择：LILRBs - 南模生物
or502通过靶向lilrb2(ilt4)，调节免疫抑制髓系细胞以恢复先天和适应性免疫反应，并可以逆转抗pd-1治疗的无响应问题。 日前，以LILRB2为代表的LILRB家族已然成为新药研发靶点的新选择。
LILRB2/PirB mediates macrophage recruitment in fibrogenesis of …
2023年7月22日 · In this study, we identified that PirB/LILRB2 were expressed in hepatic macrophages and bound with their NASH-associated ligand (ANGPTL8) to trigger the …
Leukocyte immunoglobulin-like receptor subfamily B: …
High expression of LILRB2 in DCs promotes DC tolerance, inhibits Th1 and CTL differentiation, and enhances the generation of type 2 cytokine-secreting Th2 and Tc2 cells [169,170]. …
LILRB2 leukocyte immunoglobulin like receptor B2 [ (human)]
2025年2月8日 · Mechanistically, LILRB2 enhances the SHP2/CaMK1/CREB signaling pathways to support the expansion and migration of the endometrial cancer cells. LILRB2 is …
抗癌新方向，免疫检查点LILRB - 知乎 - 知乎专栏
lilrb1和lilrb2受体通过与人白细胞抗原-g（hla-g）的相互作用抑制细胞毒性t细胞、nk细胞和b细胞，诱导t细胞无能，调节骨髓细胞，并促进tregs细胞。 此外， HLA-G 在抗原呈递细胞， …
抑制性白细胞免疫球蛋白样受体：LILRB - 知乎 - 知乎专栏
抑制性白细胞免疫球蛋白样受体（The leukocyte Ig-like receptor subfamily B LILRB）是一类一次跨膜的糖蛋白，该类蛋白的胞外区有免疫球蛋白类似（Ig-like）的结构域，胞内区域有 ITIM基 …
LILRB2 leukocyte immunoglobulin like receptor B2 [Homo …
Title: Placental Malaria is Associated with Higher LILRB2 Expression in Monocyte Subsets and Lower Anti-Malarial IgG Antibodies During Infancy. Antibody-Mediated LILRB2-Receptor …
LILRB靶点研发：行而不辍，未来可期 - 知乎 - 知乎专栏
io-108是以明生物自主开发的一款靶向lilrb2的全新抑制性抗体，可以以高亲和力和特异性结合lilrb2，并阻断lilrb2在肿瘤微环境中与癌症免疫抑制相关的配体的相互作用。