2024年8月18日 · 采用果蝇细胞系RNAi干扰的方法，作者从果蝇所有的179个E3泛素连接酶中发现只有Hyd （Hyperplastic discs） 的敲低会抑制Lin诱导的Bowl降解。有趣的是，Hyd是首个在果蝇里鉴定出来的肿瘤抑制因子，发现于1977年，但是Hyd如何抑制组织生长尤其它的关键底物至今未 …

2024年7月7日 · Here we show that hyperplastic disc (Hyd), one of the first tumor suppressors isolated genetically in Drosophila and encoding an E3 ubiquitin ligase with hitherto unknown substrates, and Lines (Lin), best known for its role in embryonic segmentation, define an obligatory tumor suppressor protein complex (Hyd–Lin) that targets the zinc finger ...

Ribonuclease A is presented below as an example of how surface water, by repetitively forming picosecond cubic ice linear elements of hydration on lipid and poly-ionic surfaces of its polypeptide, not only assists in directing and driving its wrapping and assembly into its protein structure, but its enzymatic properties as well.

2024年10月30日 · Here we show that hyperplastic disc (Hyd), one of the first tumor suppressors isolated genetically in Drosophila and encoding an E3 ubiquitin ligase with hitherto unknown substrates, and Lines (Lin), best known for its role in embryonic segmentation, define an obligatory tumor suppressor protein complex (Hyd-Lin) that targets the zinc finger ...

The Lin-Zhi International, Inc. (LZI) Hydrocodone Enzyme Immunoassay is intended for the qualitative and semi-quantitative determination of hydrocodone in human urine at a cutoff value of 100 ng/mL. The assay is designed for prescription use with a number of automated clinical chemistry analyzers.

Identification of Hyd as a critical E3 ubiquitin ligase mediating Lin-induced Bowl degradation. (A) Schematic diagram of a pooled RNAi screen for E3 ligases required for Lin-induced Bowl degradation.

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2024年8月20日 · Here we show that hyperplastic disc (Hyd), one of the first tumor suppressors isolated genetically in Drosophila and encoding an E3 ubiquitin ligase with hitherto unknown substrates, and Lines (Lin), best known for its role in embryonic segmentation, define an obligatory tumor suppressor protein complex (Hyd-Lin) that targets the zinc finger ...

Here we show that hyperplastic disc (Hyd), one of the first tumor suppressors isolated genetically in Drosophila and encoding an E3 ubiquitin ligase with hitherto unknown substrates, and Lines (Lin), best known for its role in embryonic segmentation, define an obligatory tumor suppressor protein complex (Hyd–Lin) that targets the zinc finger ...

2008年8月1日 · .fac，.hyd， .lin 里面数据是如何与网格以及网格上的结点相对应的，都看不太懂。 1*J#:| ( { ( . 问题1：HFSS网格数据怎么从HFSS中导出？ 问题2：我在.results文件中找到文件夹 imeh和cmesh，这两个里面应该都是网格数据，但是里面的文件用文本文件打开后，都读不太懂。 .fac，.hyd， .lin 里面数 ..