Lauryl maltose neopentyl glycol (LMNG) is a detergent that can solubilize and stabilize membrane proteins. Lauryl maltose neopentyl glycol extracts integral membrane proteins from membranes, and improves substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes [1] [2] .

2022年5月13日 · GLUT4 purified in β-NG gave rise to a decent initial reference and the 3D EM reconstruction was refined to 4.1 Å resolution. 3D EM reconstructions of GLUT4 in LMNG/CHS and nanodisc both reached...

lmng/chs 溶液 (10:1) Thermo Scientific 十二烷基麦芽糖新戊二醇 (LMNG) 是一种两亲性去污剂，最适合促进整合膜蛋白的增溶，同时保持结构完整性和活性。 十二烷基麦芽糖新戊二醇 (LMNG)

Lauryl Maltose Neopentyl Glycol (LMNG) is an amphiphilic detergent ideally suited to improve solubilization of integral membrane proteins while maintaining structural integrity and activity. LMNG has two linked hydrophobic chains of equal length and two hydrophilic maltoside groups to better mimic the integral membrane protein environment.

2022年4月14日 · This review introduces a treasure trove of new detergents developed over the last decade, including the very successful OGNG, LMNG, and GDN molecules. We cover a detailed analysis of their self-association properties, giving a rationale for detergent protein stabilization efficacy based on detergent-protein and detergent-detergent interactions ...

CAS Number: LMNG: [1257852-96-2] / CHS: [102601-49-0] Formula Weight: LMNG: 1005.19 / CHS: 607.9. Storage Conditions: -20oC. Appearance: Clear Solution.

LMNG/CHS Solution (10:1) is a ready-to-use formulation for the solubilization of integral membrane proteins while maintaining structural integrity and activity. The stable pre-formulated solution contains a mixture of lauryl maltose neopentyl glycol (LMNG) (5%) and cholesteryl hemisuccinate (CHS) (0.5%) in deionized water.

月桂果糖新戊二醇（lmng）带有两条等长的连接疏水链和两个亲水麦芽糖苷基团。 它引起了膜蛋白生物化学领域的强烈兴趣，因为它比通常使用的十二烷基麦芽吡喃糖苷（DDM）更好地有效地溶解和稳定了膜蛋白，并且可以确定某些具有挑战性的膜蛋白的结构。

2019年5月1日 · In this work, LMNG was shown to display a set of very interesting features: to extract integral membrane proteins from membranes; to improve substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes.