
Nature子刊:浙江大学段树民院士团队揭示神经病理性疼痛发生的关键脑区|Nature|浙江大学|LPBN…
2020年11月25日,浙江大学 段树民 院士团队在 Nature Communications 杂志发表了题为: Parabrachial nucleus circuit governs neuropathic pain-like behavior 的研究论文。 研究团队利 …
段树民团队连续在Neuron、elife和Glia等杂志发表研究成果
2020年11月28日 · 课题组研究人员利用神经病理性疼痛模型(CPN)小鼠,结合在体神经元钙信号检测、电生理、光遗传学及行为学检测等,发现在给与神经病理性痛小鼠触觉和热刺激 …
Lateral Parabrachial Nucleus - an overview - ScienceDirect
The LPBN consists of a complex of neurons in the dorsolateral pons and it plays an important role in mediating a variety of visceral functions such as taste, respiration, central cardiovascular …
Parabrachial Complex: A Hub for Pain and Aversion
2019年10月16日 · Medial PBN (mPBN) comprises populations of neurons heterogeneous in size and morphology, whereas lateral PBN (lPBN) includes several homogeneous groups. The …
Excitatory neurons in the lateral parabrachial nucleus mediate the ...
2023年12月10日 · The LPBN is a crucial component of the ascending pain pathways and may participate in the interruptive effect of pain on attention. In the LPBN, Ca 2+ /calmodulin …
Divergent Neural Pathways Emanating from the Lateral …
2020年6月17日 · The lateral parabrachial nucleus (lPBN) is a major target of spinal projection neurons conveying nociceptive input into supraspinal structures. However, the functional role …
Activation of parabrachial nucleus - ScienceDirect
2021年11月2日 · Further studies establish a pathway of glutamatergic projections from the spinal trigeminal subnucleus caudalis (Sp5C) to the lateral parabrachial nucleus (LPBN) and then to …
A Parabrachial-Hypothalamic Cholecystokinin Neurocircuit Controls ...
Here we demonstrate that lateral parabrachial nucleus cholecystokinin (CCK LPBN) neurons are a population of glucose-sensing cells (glucose inhibited) with counterregulatory capacity.
Excitatory neurons in the lateral parabrachial nucleus mediate the ...
2023年12月10日 · Activation of excitatory neurons in the LPBN is a mechanism by which acute inflammatory pain disrupts sustained attention. This finding has implications for the treatment …
找到调控神经性疼痛的臂旁核微环路 - 科学网
位于脑桥的外侧臂旁核(LPBN)被认为是脊髓向脑内传送疼痛信息的中继站,其中向脑内杏仁核传送的信息引起疼痛的情绪反应。 “我们的研究表明LPBN在传递疼痛信息的同时,还对疼痛 …