2023年10月19日 · What is the typical composition of the background of lymphocyte rich classic Hodgkin lymphoma (LRCHL) with nodular pattern? Small atypical B cells: CD20+, BCL2+, BCL6+, CD10+ Small B cells: CD20+, CD5+, CD23+, LEF1+

富含淋巴细胞的经典霍奇金淋巴瘤 (LRCHL) 的特征是呈结节性或有时呈弥漫性，主要由小 淋巴细胞 （一种 白细胞). 中性粒细胞 和 嗜酸性粒细胞 （其他类型的白细胞）通常不存在。 在结节病例中，结节会压迫周围组织，并可能含有 生发中心 （区域 B细胞 发育的细胞）较小或萎缩。 Reed-Sternberg 细胞主要存在于结节中，但在生发中心之外。 LRCHL 可能与结节性淋巴细胞为主型霍奇金淋巴瘤 (NLPHL) 混淆。 然而，具有某些典型霍奇金淋巴瘤特征的 Reed-Sternberg 细胞 …

2006年1月1日 · The results suggested that LRCHL may be associated with early stage disease and favorable prognostic factors compared with nodular sclerosis (NS) and mixed cellularity (MC) subtypes, leading to better overall survival.

2018年9月30日 · 霍奇金淋巴瘤（Hodgkin lymphoma, HL）是一种来源于单克隆B细胞的肿瘤，分为结节性淋巴细胞为主型霍奇金淋巴瘤（nodular lymphocyte predominant Hodgkin lymphoma, NLPHL）和经典型霍奇金淋巴瘤（classical Hodgkin lymphoma, CHL）。 后者又分为四种组织学亚型：结节硬化型经典霍奇金淋巴瘤 (NSCHL)、淋巴细胞丰富型经典霍奇金淋巴瘤 (LRCHL)、混合细胞型经典霍奇金淋巴瘤 (MCCHL)、淋巴细胞消减型经典霍奇金淋巴瘤 (LDCHL)。

2018年11月13日 · 霍奇金淋巴瘤（Hodgkin lymphoma, HL）是一种来源于单克隆B细胞的肿瘤，分为结节性淋巴细胞为主型霍奇金淋巴瘤（nodular lymphocyte predominant Hodgkin lymphoma, NLPHL）和经典型霍奇金淋巴瘤（classical Hodgkin lymphoma, CHL）。 后者又分为四种组织学亚型：结节硬化型经典霍奇金淋巴瘤 (NSCHL)、淋巴细胞丰富型经典霍奇金淋巴瘤 (LRCHL)、混合细胞型经典霍奇金淋巴瘤 (MCCHL)、淋巴细胞消减型经典霍奇金淋巴瘤 (LDCHL)。

LR CHL is a subtype of CHL in which there is a predominance of small lymphocytes. It typically has a nodular or, less commonly, a diffuse cellular background. It is also characterized by the absence of eosinophils and neutrophils. LR CHL shares many of the clinical aspects of NLP HL, features which are distinct from those of other forms of CHL.

2009年5月22日 · In this study, we have carried out a comparative marker analysis of lymphocyte-rich classical Hodgkin's lymphoma, nodular lymphocyte-predominant Hodgkin's lymphoma, and other classical Hodgkin's...

2019年1月17日 · Lymphocyte-rich classical Hodgkin lymphoma (LRCHL) is a rare histologic subtype of classical Hodgkin lymphoma (CHL) comprising about 5% of all CHL cases. Patients...

Background: To investigate the proportion, clinical characteristics and outcome of lymphocyte-rich classical Hodgkin lymphoma (LRCHL) in relation to nodular lymphocyte predominant HL (NLPHL) and classical HL (cHL).

2016年4月1日 · The HRS cells show broad morphologic spectrum: a proportion of the HRS cells may resemble lymphocyte predominant (LP) cells or mononuclear lacunar cells. However, the demonstration of an immunophenotype typical for classical HRS cells may permit their precise recognition as LRCHL tumour cells.