Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme that in humans is encoded by the MAP2K1 gene. [5][6] The protein encoded by this gene is a member of the …

2024年12月25日 · MAP2K1 (Mitogen-Activated Protein Kinase Kinase 1) is a Protein Coding gene. Diseases associated with MAP2K1 include Cardiofaciocutaneous Syndrome 3 and …

The MAP2K1 gene provides instructions for making a protein known as MEK1 protein kinase. This protein is part of a signaling pathway called the RAS/MAPK pathway, which transmits …

MAP2K1, also known as MAPK/ERK kinase 1 (MEK1), is a serine/threonine and tyrosine kinase that is activated by RAF kinases. The structure of human MAP2K1 protein consists of a central …

This is the first report of MAP2K1 mutations in Langerhans cell histiocytosis(LCH) that occur in 50% of BRAF wild-type cases. The mutually exclusive nature of MAP2K1 and BRAF mutations …

At least three mutations in the MAP2K1 gene have been identified in people with melorheostosis. This rare disease causes the abnormal growth of new bone tissue on the surface of existing …

Mitogen-activated protein (MAP) kinases, also known as extracellular signal-regulated kinases (ERKs) (see ERK2, or MAPK1; 176948), are thought to act as an integration point for multiple …

MAP2K1 (MEK1), mitogen-activated protein kinase kinase 1, is a serine-threonine kinase, which activates the RAS-RAF-MEK-ERK pathway in cell proliferation and differentiation (PMID: …

2015年10月13日 · Clinical resource with information about MAP2K1, Cardiofaciocutaneous syndrome 3, Melorheostosis, Noonan syndrome, Noonan syndrome 1, and available tests. …

2024年6月17日 · Title: MAP2K1-mutated melanocytic tumors have reproducible histopathologic features and share similarities with melanocytic tumors with BRAF V600E mutations. …