
Fas signaling in adipocytes promotes low-grade inflammation …
2021年12月1日 · The results of our study indicate that obesity contributes to lung metastasis in the MC38 colon cancer cells and that the Fas signaling in adipocytes promotes lung …
Fas signaling in adipocytes promotes low-grade inflammation …
2021年12月1日 · In this study, we found that the increased tumor necrosis factor-alpha (TNF-α) in adipocytes promoted the lung metastasis of MC38 colon cancer cells via Fas signaling.
Loss of Fas Expression and Function Is Coupled with Colon Cancer ...
2019年2月1日 · Fas expression level in subsets of colon cancers was compared in murine colon carcinoma CT26, MC32a, and MC38 cell lines and human colon carcinoma HCT116 and …
Reprogramming immunosuppressive myeloid cells by activated …
2021年1月8日 · To confirm the role of reprogramming MDSCs by activated T cells in vivo, we tested the effect of PD-1 mAb on the survival and function of tumor-infiltrating myeloid cells in …
PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid …
2020年10月20日 · The improved outcome of MC38-OT I tumors treated with GW6471-PD-L1 antibody combination therapy prompted us to test whether DCs play a major role in this anti …
Tumor-infiltrating monocytes/macrophages promote tumor …
2016年4月18日 · In this study, we report that monocytes/macrophages induce S100a8 and S100a9 messenger RNA (mRNA) expression in cancer cells in an extracellular signal-related …
Irradiation of tumor cells up-regulates Fas and enhances CTL lytic ...
2003年6月15日 · Treatment of carcinoembryonic Ag-expressing MC38 adenocarcinoma cells with irradiation (20 Gy) in vitro enhanced Fas expression at molecular, phenotypic, and functional …
中国科学院典型培养物保藏委员会细胞库/中国科学院上海生命科学 …
MC38细胞表达claudin-1和SATB2等结肠标志物,这对于研究结肠腺癌的基因组和表观基因组以及探寻潜在的治疗手段至关重要。 MC38异种移植模型的免疫学特性使其成为癌症研究的通用工 …
mc38异种移植模型的免疫学特性使其成为癌症研究的通用工具。 物种:小鼠,C57BL/6品系;雌性 组织:结肠;疾病:结肠腺癌
Oncolytic poxvirus armed with Fas ligand leads to induction of …
Infection of FasR+ normal and MC38 cancer cells by vFasL led to abortive viral replication owing to acute apoptosis and subsequently showed both reduced pathogenicity in non-tumor-bearing …