2004年1月2日 · mk-801 trip report, all systems go 200ml=10mg 20ml=1mg 2ml=100um 1ml=50um the first shot of 50um IM had little effect, some tinnitus. i lay down and experienced a definited slowing of myheart, part of kprogramming. some slow strobing visual effects and CEV, onset in about 25min. got a sex...

2008年5月24日 · recently acquired (+)-mk-801 maleate as well as freebase from very reputable source. I was kind of hoping the base would be liquid so i could dilute it with a solvent like ether and smoke it like pcp (i miss my pcp days...). I opened the vial of freebase which was a powder and decided to sample that 1st.

2015年1月26日 · Mk-801 Sounds like MK-801 is a most worthy and wonderful vehicle for self-discovery and bliss. I am a fan of 3-meO-PCP and especially appreciate the lack of baggage in social situations. Amazing ability to connect and communicate with others. Also enjoy the uplift I get on the day after an excursion. No clouds, no fog, just sweet lucidity.

2022年3月31日 · I would say that the reports on MK-801 overall do not sound very positive, but they are extremely interesting, and I remember reading one more recent one (which could mean anytime in the last 10 years because time is weird), where the author really liked it. It sounds like a very weird drug. Certainly not an MXE replacement at all, though.

2011年10月10日 · However, following parenteral administration, dizocilpine maleate (MK-801), ketamine, PCP, dexoxadrol, and 1-(2-thienyl)cyclohexylpiperidine HCl, but not tiletamine, increased rat pyriform cortical DA metabolism and/or release, a response modulated by the NMDA-uncoupled PCP recognition sites.

2004年4月21日 · Dextromethorphan is one of the most fascinating drugs I have ever encountered--it has a bewildering array of psychical/phenomenological effects, including dissociative, empathoogenic, stimulant, depressant, psychedelic, euphoric and dysphoric qualities. In myself, dextromethorphan often...

2012年2月24日 · One 3-MeO-PCP variant I had felt like a woodhammer dissociative, not psychedelic at all and just heavily dissociative, a bit like I suppose MK-801 to be. Other batch was very psychedelic and threw me directly into one of the very few holes I ever had. This batch was also much more potent and hard to dose correctly.

2010年11月4日 · This is said to be what happens with MK-801 and other NMDA antagonists, too. Blockade of morphine- and amphetamine-induced conditioned place preference in the rat by riluzole Previous studies have shown that antagonists at glutamatergic N-methyl-d-aspartate (NMDA) or α-amino-3-hydroxy-5-methyl-4-isoxazolpropionic acid (AMPA…

1999年11月3日 · I think this was tried in the 1960s. R.D Laing was certainly using LSD. Anti-psychiatry was the field most interested in their use. Of course, LSD does not replicate schizophrenia - MK-801 and it's ilk do that,

2016年1月5日 · 290 nM ([3H]-MK-801, rat cortex homogenate) (Stefek et al. 1990), 140 nM ([3 H] PCP, rat brain homogenate) (Kozlowski et al. 1986), and 200 nM ([3H]PCP, rat brain homogenate) (Zukin and Zukin 1979). Displacement studies of [3H]PCP-specific binding in rat olfactory bulb slices revealed PCPy (IC50 1⁄4 65 nM) to be more potent