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2022年12月19日 · Blood-brain barrier (BBB) breakdown and immune cell infiltration into the CNS are early hallmarks of multiple sclerosis (MS). The mechanisms leading to BBB dysfunction are incompletely understood and generally thought to be a consequence of neuroinflammation. Here, we have challenged this view and a …

Dysregulation of the BBB and transendothelial migration of activated leukocytes are among the earliest cerebrovascular abnormalities seen in multiple sclerosis (MS) brains and parallel the release of inflammatory cytokines/chemokines.

2024年5月5日 · 至此，访问 /aaa/hello 会返回 hello from ms_aaa，而 /bbb/hello 会返回 hello from ms_bbb。 源码查看 example_nest_nacos 仓库，拜~。 大胆的番茄

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MS exhibits many of the hallmarks of an inflammatory autoimmune disorder including breakdown of the blood-brain barrier (BBB). The BBB is a complex organization of cerebral endothelial cells, pericytes and their basal lamina, which are surrounded and supported by astrocytes and perivascular macrophages.

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2014年11月1日 · MS exhibits many of the hallmarks of an inflammatory autoimmune disorder including breakdown of the blood–brain barrier (BBB). The BBB is a complex organization of cerebral endothelial cells, pericytes and their basal lamina, which are surrounded and supported by astrocytes and perivascular macrophages.