2024年12月25日 · MST1 (Macrophage Stimulating 1) is a Protein Coding gene. Diseases associated with MST1 include Immunodeficiency 14 and Cholangitis, Primary Sclerosing . …

Mammalian Mst1 and Mst2 kinases play essential role in the regulation of cellular redox state. See text for details.

2013年8月28日 · The serine/threonine protein kinases Mst1 and Mst2, mammalian homologs of the Hippo kinase from Drosophila, play the central roles in the Hippo pathway controlling the …

2024年11月22日 · MST1 knockdown and chemical inactivation reduced cognitive decline, mitochondrial dysfunction, and neuronal degeneration. Mechanistically, MST1 regulated the …

Mammalian STE20-like kinase-1 (Mst1) is a generally expressed apoptosis-promoting kinase and a key bridge-builder of apoptotic signaling in the etiology of tissue injury.

Mammalian sterile 20-like kinase 1 (MST1) is a protein kinase, and the occurrence of many heart diseases is related to the continuous activation of the MST1 gene. With the deepening of the …

MST1 or MST2 overexpression was also found to consistently induce apoptosis; moreover, apoptosis activated the endogenous MST1/MST2 kinases, 4–9 responses suggestive of a …

2025年1月4日 · Title: Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice. Macrophage-stimulating protein is decreased in severe …

2024年7月25日 · Here we show that Mst1 phosphorylates FoxO1 Ser209/Ser215/Ser218/Thr228/Ser232/Ser243, thereby inhibiting FoxO1-mediated …

2014年3月16日 · We show MST1 as a proapoptotic kinase and key mediator of apoptotic signaling and beta cell dysfunction and suggest that it may serve as target for the development …