2024年12月25日 · MSX1 (Msh Homeobox 1) is a Protein Coding gene. Diseases associated with MSX1 include Witkop Syndrome and Orofacial Cleft 5. Among its related pathways are Gastrulation and Nervous system development. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and p53 …

Homeobox protein MSX-1, is a protein that in humans is encoded by the MSX1 gene. [5][6] MSX1 transcripts are not only found in thyrotrope-derived TSH cells, but also in the TtT97 thyrotropic tumor, which is a well differentiated hyperplastic tissue that produces both TSHß- and a-subunits and is responsive to thyroid hormone.

2016年7月6日 · In humans, MSX1 variants have been related to tooth agenesis, orofacial clefting, and nail dysplasia. We correlate all MSX1 disease causing variants to phenotypic features to shed light on this...

2025年1月22日 · Here, we show that MSX1 phase separation is a vertebrate-conserved mechanism underlying embryonic palatal fusion. Notably, MSX1 phase separation is triggered by its intrinsically disordered...

The MSX1 gene provides instructions for making a protein that regulates the activity of other genes. The MSX1 gene is part of a larger family of homeobox genes, which control the formation of many body structures during early development.

2025年2月8日 · Title: Characterization of novel MSX1 variants causally associated with non-syndromic oligodontia in Chinese families. MSX1 involved selective tooth agenesis and abnormal labial frenum, pedigree, and retrospective study.

关于 msx1 Cytogenetic location: 4p16.2 Genomic coordinates (GRCh38): 4:4,859,665-4,863,936 (from NCBI) This gene has 2 transcripts (splice variants), 127 orthologues, 1 paralogue and is associated with 10 phenotypes.

2003年12月1日 · Msx1 is common to multiple growth factor signaling pathways and serves in the orchestration of inductive events essential to organogenesis. Therefore, we find its repeated use in the BMP, FGF ...

2022年9月5日，浙江大学欧阳宏伟团队在Nature Communications在线发表了题为 “Msx1+ stem cells recruited by bioactive tissue engineering graft for bone regeneration”的研究论文。...

Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus. Characterization of novel MSX1 variants causally associated with non-syndromic oligodontia in Chinese families. MSX1 involved selective tooth agenesis and abnormal labial frenum, pedigree, and retrospective study.