Human Mitochondrial RNA Processing and Modifications: Overview
Mitochondrial DNA (mtDNA) contains 37 genes that encode 13 subunits of the oxidative phosphorylation (OXPHOS) system, two ribosomal RNAs (rRNAs), and 22 transfer RNAs …
Complete chemical structures of human mitochondrial tRNAs
2020年8月28日 · Twenty-two species of mitochondrial (mt-)tRNAs encoded in mtDNA translate essential subunits of the respiratory chain complexes. mt-tRNAs contain post-transcriptional …
Structural basis of mitochondrial translation - PubMed
2020年8月19日 · Translation of mitochondrial messenger RNA (mt-mRNA) is performed by distinct mitoribosomes comprising at least 36 mitochondria-specific proteins. How these …
Transcription, Processing, and Decay of Mitochondrial RNA in …
Once transcribed, mitochondrial RNA (mtRNA) is processed, mito-ribosomes are assembled, and mtDNA-encoded proteins belonging to the respiratory chain are synthesized.
线粒体转移核糖核酸（mt-tRNA）的牛磺酸修饰——纪念邹承鲁先 …
2023年5月11日 · 研究表明，5-牛磺酸甲基尿嘧啶核苷（5-taurinomethyluridine，τm 5 U）修饰只存在于高等真核生物mt-tRNA第34位，能够调节密码子和反密码子相互作用的精确性，控制翻 …
Mitochondrial genetics, signalling and stress responses
2025年3月10日 · Recent methodological developments have enabled the analysis of mitochondrial DNA (mtDNA) in large-scale cohorts and highlight the far-reaching impact of …
Molecular basis of human nuclear and mitochondrial tRNA 3
2025年1月2日 · In humans, ELAC2 carries out 3′ end processing of both nucleus-encoded (nu-tRNAs) and mitochondria-encoded (mt-tRNAs) tRNAs. ELAC2 is self-sufficient for processing …
MT-RNR1 RNA Gene - GeneCards
2024年12月25日 · MT-RNR1 (Mitochondrially Encoded 12S RRNA) is an RNA Gene, and is affiliated with the rRNA class. Diseases associated with MT-RNR1 include Rare Mitochondrial …
MT-RNR1 - an overview | ScienceDirect Topics
Polycistronic RNA initiating from H1 starts upstream of MT-TF, the gene encoding mt-tRNA Phe and has a defined termination site within MT-TL1 (mt-tRNA Leu(UUR)). The longer …
Human mitochondrial tRNAs: biogenesis, function, structural …
Human (mammalian) mtDNA encodes 13 essential subunits of the inner membrane complex responsible for OXPHOS. These mRNAs are translated by the mitochondrial protein synthesis …