2014年12月6日 · The key objectives of these first-in-human, Phase I, randomized, double-blind, placebo-controlled single (SAD) and multiple ascending dose (MAD) studies are to identify a safe and pharmacodynamically-active dose and schedule for AG-348 to be used in subsequent clinical studies in subjects with PKD [NCT02108106; NCT202149966].

Pyruvate kinase deficiency is a chronic hemolytic anemia caused by mutations in PK-R, a key glycolytic enzyme in erythrocytes. These 2 phase 1 randomized, placebo-controlled, double-blind healthy-volunteer studies assessed the safety, tolerability, and pharmacokinetics/pharmacodynamics of AG-348, a …

2014年12月6日 · The key objectives of these first-in-human, Phase I, randomized, double-blind, placebo-controlled single (SAD) and multiple ascending dose (MAD) studies are to identify a safe and pharmacodynamically-active dose and schedule for AG-348 to be used in subsequent clinical studies in subjects with PKD [NCT02108106; NCT202149966].

2025年2月21日 · MAD MAGAZINE #348 VG 1996 EC (FREE SHIP ON $15 ORDER!) A book that does not look new and has been read but is in excellent condition. No obvious damage to the cover, with the dust jacket (if applicable) included for hard covers. No missing or damaged pages, no creases or tears, and no underlining/highlighting of text or writing in the margins.

Read reviews and discussion of Mad #348, published by EC Comics

MAD MAGAZINE #348 FINE- 1996 EC (FREE SHIP ON $15 ORDER!) Breathe easy. Returns accepted. US $5.99Standard Shipping. See details. 14 days returns. Buyer pays for return shipping. See details. Special financing available. See terms and apply now. Earn up to 5x points when you use your eBay Mastercard®. Learn more.

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2014年12月31日 · Mad Magazine #348 August 1996Doug Gilford's MadCoverSite.com listinghttps://madcoversite.com/mad348.html

1996年8月10日 · Explore detailed information and market values for Mad #348 comic book, including current prices, sales data, and collector insights.

# 347 # 348 # 349 # 350 # 351 # 352 # 353 # 354 # 355 # 356 # 357 # 358 # 359 # 360 # 361 # 362 # 363 # 364 # 365 # 366 last edited by mshirley27 on 02/07/22 05:50PM ...