Map2是成熟神经元特异性Marker。 将2A-CreERT2共表达结构插入小鼠内源Map2基因3'UTR之前。 应用领域 ：神经系统，成熟神经元Cre重组酶

Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic marker. It …

2025年2月8日 · Increased MAP2 expression in malignant melanoma cells significantly inhibits tumor cell growth and neoplasm invasiveness, and induces apoptosis and cell cycle arrest. …

2001年10月1日 · MAP1B and MAP2 are major members of neuronal microtubule-associated proteins (MAPs). To gain insights into the function of MAP2 in vivo, we generated MAP2 …

2004年12月23日 · Knockout mice show that MAP2 is essential for linking PKA to microtubules in various brain regions . Interestingly, the absence of MAP2 affects the phosphorylation of …

Using immunocytochemistry with antibodies and in situ hybridization histochemistry with [32P] labeled oligonucleotide probes, we examined the cellular localization of MAP2, GAP-43 and …

1996年5月5日 · To learn more about its potential effects on neuronal morphogenesis and its sorting within the neuronal cytoplasm, we have raised transgenic mice that express high levels …

2024年12月30日 · In infected mice immunoreactivity to MAP2 was intense in somas and dendrites of Purkinje cells and in some interneurons. These results are consistent with similar …

Microtubule Associated Protein 2 (MAP2) is a protein that is specific to neurons and plays a crucial role in maintaining the structural integrity of the cytoskeleton and regulating various …

View mouse Map2 Chr1:66214432-66481742 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression