2024年11月1日 · The distribution of lung cancer growth rates is categorized into rapid growth (VDT≤400 days), slow growth (VDT>400 days), and shrinkage (VDT<0 days), as observed across various studies. The latter two categories are collectively referred to as indolent lung cancer, defined as VDT> 400 or < 0 days.

Growth rate is an independent risk factor for lung cancer in screened pulmonary nodules. This study aimed to clarify growth characteristics of pulmonary nodules in routine clinical practice and examine whether volume doubling time (VDT) can predict the malignancy of these nodules.

Purpose: To evaluate volume doubling time (VDT) and mass doubling time (MDT) of persistent pulmonary subsolid nodules (SSNs) followed-up with low-dose (LD) computed tomography (CT) in patients without a history of malignancy.

1、 体积倍增时间 （volume double time，VDT）：肺结节体积增大一倍所需要的时间。 2、 质量倍增时间 （mass double time，MDT）。 即肿瘤质量增大 1 倍所需要的时间，常用于随访过程中描述结节的生长速率。

2024年2月4日 · 本研究旨在比较有无驱动基因突变的原发性侵袭性肺腺癌中VDT和质量倍增时间 (mass doubling time, MDT)的差异。 选取2019年1月—2020年12月期间在同济大学附属上海市肺科医院行手术切除且术前至少2次胸部非增强CT检查的患者作为研究对象。 纳入标准: (1) 经组织学证实的浸润性肺腺癌; (2) 切除前至少做2次胸部CT检查。 排除标准: (1) 术后未进行基因检测; (2) 新辅助治疗患者; (3) 术前可用的非增强CT少于2次; (4) 术前2次非增强CT间隔<90 d; (5) 图像质量 …

Low VDT indicates rapid growth, and a VDT of less than 400 days has recently been suggested as the best cut-off value to distinguish between ‘indolent’ and malignant lesions (14,15). Opinions have also been expressed that lung cancers with a VDT of …

摘要 目的比较伴或不伴基因突变的原发性肺腺癌在体积倍增时间(volume doubling time,VDT)和质量倍增时间(mass doubling time,MDT)间的差异。方法选取2019年1月—2020年12月在同...

Three-dimensional semiautomatic segmentation of nodules was performed to calculate the volume doubling time (VDT), mass doubling time (MDT), and specific growth rate (SGR) of volume and mass. Multivariate linear regression, one-way analysis of variance, and receiver operating characteristic curve analyses were performed.

2024年5月13日 · Volume doubling time is defined as the time required for a growing nodule to double its volume. A longer VDT suggests a more benign course, whilst a short VDT is indicative of a more aggressive lesion with higher histological grade.

In the 44 patients with squamous cell carcinoma, the mean VDT was 133 days, and only 2.3% of these patients had a VDT of more than 400 days. These results were different from those previously reported for CT screening.