Von Willebrand factor (VWF), a multimeric glycoprotein, has long been implicated in ischemic stroke pathology 2, 3. ... MCAO/R was performed by introducing a silicone-coated …

2022年11月3日 · von Willebrand factor (VWF) is a large sialoglycoprotein that circulates in normal plasma as a series of heterogeneous multimers 1,2.For many years, the importance of plasma …

2022年3月10日 · Significant restoration of rCBF and reduced lesion volume was observed in animals treated with caADAMTS13. When administered 1 hour after FeCl3 MCAo, the …

(MCAO). At day 3 after MCAO and reperfusion, we found an in-crease in 18F-FDG uptake in the aorta (Figure 1C), ... Cluster 1 highly expressed Vcam1, Vwf, and other genes such as Cytl1 …

2016年10月26日 · von Willebrand factor (VWF) is an ultra-large multimeric glycoprotein, which is present in Weibel-Palade bodies of endothelial cells and alpha granules of platelets and is …

2003年6月15日 · vWF immunohistochemistry in DG and caudate-putamen (CPu) from control rats (Con) and 1 week after MCAO (Isch) or MCAO plus VEGF treatment (Isch + VEGF). For the …

2006年10月12日 · When animals were cotreated with the angiogenesis inhibitor endostatin for 14 days starting 1 day after MCAo, the effect of running on BrdUrd + and vWF-associated BrdUrd …

我们发现，TSP4-BMSC输注可促进中风后神经功能的恢复。经tsp4基因修饰的骨髓间充质干细胞比野生型骨髓间充质干细胞具有更好的治疗效果。TSP4-BMSC输注改善了MCAO大鼠的神经 …

Introduction: We demonstrated that VWF inhibition thrombolyses stabilized clots in and decreases infarct size after middle cerebral artery occlusion (MCAO) in pre-clinical models of stroke. …

2022年3月10日 · When administered 1 hour after FeCl 3 MCAo, the caADAMTS13 variant significantly reduced residual VWF and fibrin deposits in the MCA, platelet aggregate …