
Why we need female mice in neuroscience research - Harvard …
2023年3月8日 · Researchers found that female mice, despite ongoing hormonal fluctuations, exhibit exploratory behavior that is more stable than that of their male peers, countering the belief that the hormone cycle in females causes behavioral variation that could throw off results.
Of Mice and Women: The Bias in Animal Models | Science - AAAS
Male rats and mice have become the default animal model for many diseases because they are easier and cheaper to work with than females. Female rodents have a 4-day ovarian cycle, so researchers who use them must take daily vaginal swabs in …
Mimicking women’s endocrine milieu in mice for women’s
2025年2月22日 · We show that female mice of NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) strain widely used for PDXs has 17-β-estradiol (E2) and testosterone (T) levels comparable to C57Bl6 females but higher...
Of Mice and Women: How a Genomic Experiment Unveiled …
2025年4月8日 · This fascinating desert-adapted species is capable of living its entire life without ever drinking water or urinating. Within the lab, both undergraduate and graduate students are pursuing a variety of different experiments studying this mouse.
The Case for Female Mice in Neuroscience Research
2023年3月7日 · Historically, researchers have favored male mice over female mice in experiments, in part due to concern that the hormone cycle in females causes behavioral variation that could throw off results. But new research from Harvard Medical School challenges this notion and suggests that for many experiments, the concern may not be justified.
Male rats and mice have become the default animal model for many diseases because they are easier and cheaper to work with than females. Female rodents have a 4-day ovarian cycle, so researchers who use them must take daily vaginal swabs in …
Guess Which Sex Behaves More Erratically (at Least in Mice)
2023年3月7日 · A new study finds male mice more unpredictable than females, challenging century-old assumptions used to exclude females from research because of their hormones.
Female mice liberated for inclusion in neuroscience and …
2014年3月1日 · Inclusion of female mice in neuroscience research is justifiable and desirable. The underrepresentation of female mice in neuroscience and biomedical research is based on the assumption that females are intrinsically more variable than males and must be tested at each of four stages of the estrous cycle to generate reliable data.
Of Mice and Women - ScienceDirect
This book is a comprehensive compilation and discussion of research findings on female aggression from anthropology, social psychology, animal research, case studies, and representations in literature.
Opinion | Why Science Needs Female Mice - The New York Times
2015年7月18日 · A new study published in the journal Nature Neuroscience suggests that research done on male animals may not hold up for women. Its authors reported that hypersensitivity to pain works...