
MINK1 - Wikipedia
Misshapen-like kinase 1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may …
MINK1 Gene - GeneCards | MINK1 Protein | MINK1 Antibody
2024年12月25日 · MINK1 (Misshapen Like Kinase 1) is a Protein Coding gene. Diseases associated with MINK1 include Myasthenic Syndrome, Congenital, 4B, Fast-Channel and …
畸形样激酶 1(MINK1)基因 | MCE - MCE-生物活性分子大师
该基因编码属于生发中心激酶 (GCK) 家族的丝氨酸/苏氨酸激酶。 该蛋白在结构上类似于与 NIK 相关的激酶,并且可能属于 GCK 家族中 NIK 相关激酶的一个独特亚家族。 对小鼠同系物的研 …
Clinical Potential of Misshapen/NIKs-Related Kinase (MINK) 1
2024年12月5日 · MINK1 plays an important role in immunological responses, inhibiting Th17 and Th1 cell differentiation and regulating NLRP3 inflammasome function. It may be considered a …
MINK1 misshapen like kinase 1 [ (human)] - National Center for ...
2025年2月9日 · Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis. MINK1 …
Priming of NLRP3 inflammasome activation by Msn kinase MINK1 …
MINK1 deficiency reduced NLRP3 activation and suppressed inflammatory responses in mouse models of acute sepsis and peritonitis. Reactive oxygen species (ROS) upregulated the kinase …
Dual roles of misshapen/NIK-related kinase (MINK1) in ... - PubMed
MINK1 deficiency protects cartilage from degeneration in aging joints through increased SMAD2 activation in chondrocytes, while accelerating OA progress in injury-induced model through …
基于 CRISPR 的激酶组筛选显示 MINK1 作为可药性参与者通过 …
在这里,使用基于 crispr/cas9 的激酶组敲除筛选,畸形样激酶 1 (mink1) 被确定为 oscc 中 5fu 耐药性的重要介质。 临床样本分析表明,与化疗应答者相比,化疗无应答者的肿瘤组织中 …
MINK1激酶在T细胞早期发育中的功能及作用机制研究_百度百科
Mink1是利用SAGE(serial analysis of gene expression)方法,在CD4+ T细胞中筛选到的高表达基因,其编码了一个丝氨酸/苏氨酸激酶。 早期研究通过RNAi技术显示MINK1参与了T细胞的 …
畸形样激酶 1 (斑马鱼)(Mink1)基因 | MCE - MCE-生物活性 ...
与人类 mink1 同源(畸形像激酶 1)。 [由基因组资源联盟提供,2022 年 4 月] Enables ATP binding activity and protein serine/threonine kinase activity.