As mir-92 is expressed in the majority of cells at all times, its expression profiles will form a reliable part of diagnosis and detection of disease. miR-92a is also present in the blood plasma of humans along with 91 other miRNAs.

小细胞肺癌肿瘤组织中miR-92a-2 水平增高，可作 为肿瘤化疗耐药及预后的标志物。但亦有研究发现， miR-92a 在肝癌、多发性骨髓瘤及非霍奇金淋巴瘤 组织中高表达，而在患者血浆中的表达却明显低于 正常人[12-14] ；而miR-92a 在乳癌组织及外周血中均

miR-92a是一种兼具高特异性和高灵敏度的结直肠癌肿瘤标志物，通过对粪便样本内脱落肠道上皮细胞内的miR-92a含量进行荧光定量PCR检测，即可获知癌前病变及结直肠癌的风险，可作为有效的结直肠癌高风险人群筛查，大规模人群筛查、临床辅助诊断和辅助结直肠 ...

2013年11月11日 · MiR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92a-1 are members of the miR-17/92 cluster. The miR-17/92 cluster is important in cell cycle, proliferation, apoptosis and other...

2023年9月13日 · Our loss-of-function data identified miR-92a-3p as one of the best miRNAs whose knockdown is associated with cisplatin sensitivity (Fig. 1B). Fig. 1: MiRNA loss-of-function screening reveals...

2024年12月25日 · MIR92A1 (MicroRNA 92a-1) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR92A1 include Lymphoma and Leukemia, Chronic Lymphocytic. Among its related pathways is miRNAs involved in DNA damage response. ... Control Lentivectors and Lentiviruses with GFP, RFP, and Luciferase also available.

睿长太®miR-92a检测试剂盒（荧光RT-PCR法）有望蜕变升级为业内首款，经上市前回顾性对照临床试验和上市后前瞻性筛查临床试验评价，可对癌前病变分级、精准捕捉，且适用于普通人群的肠癌早筛产品。

2019年10月1日 · Correlation between miR-92a and the target gene was assessed by linkedOmics while expression of the target gene and its role in cancer prognosis were analyzed with UALCAN and Gepia. Results: We recognized the miR-92a family could serve as a potential diagnostic biomarker with a pooled sensitivity of 0.85 [0.81-0.88] and specificity of 0.86 [0. ...

2022年11月17日 · 本研究通过对miR-92a-3p的生物信息学预测分析，筛选出192个hsa-miR-92a-3p的靶基因，并通过构建靶基因集合编码蛋白质间的相互关系网络，获取关键节点靶基因，为进一步深入探究hsa-miR-92a-3p相关分子功能及作为临床诊断和检测靶标提供理论研究基础。

2025年1月23日 · 目的 探究结直肠癌(CRC)癌组织中miR-106a、miR-92a、miR-31与其新生血管生成及侵袭转移的关系.方法 选取本院2018年1月至2020年1月诊治的100例结直肠癌患者作为CRC组,另选取同期健康体检者60例作为对照组.全部均行实时荧光定量聚合酶链反应(RT-PCR)检测miR-106a、miR-92a、miR-31表达量,采用免疫组化法检测CD34表达 ...