Nature | piRNA前体产生的机制 - 知乎 - 知乎专栏
目前，人们认为核内切酶 Zucchini （小鼠中称为MitoPLD或PLD6），作为线粒体外膜蛋白，是催化pre-pre-piRNA裂解为pre-piRNA的主要酶，但是却缺乏直接证据，并且其切割方式也一直存 …
MitoPLD Is a Mitochondrial Protein Essential for Nuage Formation …
MitoPLD is a member of the phospholipase D superfamily proteins conserved among diverse species. Zucchini, the Drosophila homolog of MitoPLD, has been implicated in primary …
Mitoguardin Regulates Mitochondrial Fusion through MitoPLD …
MIGA proteins function downstream of mitofusin and interact with MitoPLD to stabilize MitoPLD and facilitate MitoPLD dimer formation. Therefore, we propose that MIGA proteins promote …
Roles for the lipid-signaling enzyme MitoPLD in mitochondrial …
In the first role, MitoPLD-generated PA regulates mitochondrial shape through facilitating mitochondrial fusion. In the second role, MitoPLD performs a critical function in a pathway that …
浙江大学佟超课题组在线粒体动态调控机制上取得重要进展
2016年1月15日 · MIGA1/2可以形成同源或异源的二聚体，并与一个调控线粒体融合的磷酯酶MitoPLD相结合。MitoPLD通过形成二聚体调控线粒体表面磷脂组成。而MIGA1/2则可以稳 …
MITOPLD is a member of the phospholipase D super-family proteins conserved among diverse species. Zucchini (Zuc), the Drosophila homolog of MITOPLD, has been implicated in primary …
NCB | 武汉大学发现低密度脂蛋白能够从内吞载体传递到线粒体支 …
磷脂酶D6 (PLD6；也称为mitoPLD)是PLD家族的一员，负责将线粒体外膜(OMM)定位的心磷脂水解成磷脂酸。 磷脂酸是一种锥形磷脂，通过脂质膜产生负曲率来促进膜融合。
MITOPLD is a mitochondrial protein essential for nuage …
2011年3月15日 · MITOPLD is a member of the phospholipase D superfamily proteins conserved among diverse species. Zucchini (Zuc), the Drosophila homolog of MITOPLD, has been …
Metabolism and function of mitochondrial cardiolipin
2014年7月1日 · MitoPLD, a divergent member of the phospholipase D (PLD) superfamily, was found to localize to the mitochondrial surface via insertion of a short N-terminal anchor into the …
A common lipid links Mfn-mediated mitochondrial fusion and …
2006年10月8日 · Mitochondrial PLD (MitoPLD) targets to the external face of mitochondria and promotes trans-mitochondrial membrane adherence in a Mfn-dependent manner by hydrolysing...