
MKNK1 Gene - GeneCards | MKNK1 Protein | MKNK1 Antibody
2024年12月25日 · MKNK1 (MAPK Interacting Serine/Threonine Kinase 1) is a Protein Coding gene. Diseases associated with MKNK1 include Glioma Susceptibility 1 and Leukemia, Acute Myeloid. Among its related pathways are Negative regulation of …
MKNK1 - Wikipedia
MAP kinase-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MKNK1 gene. [5][6] MKNK1 has been shown to interact with MAPK1 [7] and Eukaryotic translation initiation factor 4 gamma. [8] ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
MKNK1 MAPK interacting serine/threonine kinase 1 [ (human)]
MNK-1 controls chemokine secretion and proliferation in human airway smooth muscle cells. MNK1 encodes a Ser/Thr protein kinase that interacts with extracellular signal-regulated kinase 1 and p38 mitogen-activated protein kinase, a pathway that is involved in Blood Pressure regulation through norepinephrine and angiotensin II.
MAPK 相互作用的丝氨酸/苏氨酸激酶 1(MKNK1)基因 | MCE
Ubiquitous expression in appendix (RPKM 4.8), pancreas (RPKM 4.3) and 25 other tissues. 该基因编码的 Ser/Thr 蛋白激酶与 ERK1 和 p38 丝裂原活化蛋白激酶相互作用并被其激活,因此可能在对环境压力和细胞因子的反应中发挥作用。 该激酶还可以通过与 eIF4G 的 C 末端区域相互作用磷酸化 eIF4E 来调节转录。 已经注意到该基因的可变剪接转录物变体。 [RefSeq 提供,2012 年 1 月]
Mknk1 MAP kinase-interacting serine/threonine kinase 1 [Mus …
Title: Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice. Long-term potentiation (LTP) consolidation in the dentate gyrus of live rodents requires sustained (hours) BDNF-TrkB signaling and from TrkB to MAP-kinase-interacting kinase.
丝裂素活化蛋白激酶(MAPK)与激酶1和2(MNK1和MNK2)相互 …
背景:MNK1和MNK2是与MAP激酶相互作用的丝氨酸/苏氨酸激酶,被RAS和MAPK信号通路激活,并参与蛋白质翻译的调控。 两种激酶都会在保守的丝氨酸209上磷酸化翻译起始因子eIF4E …
MAP 激酶相互作用的 丝氨酸/苏氨酸激酶 1(Mknk1)基因 | MCE
该基因编码一种丝氨酸-苏氨酸蛋白激酶,可被细胞外信号调节激酶或 p38 丝裂原活化蛋白激酶激活,它可能在细胞因子和环境应激反应中发挥作用。 这种激酶是真核翻译起始因子 4E 磷酸化所必需的,但它不是发育过程中细胞生长所必需的。 该基因的可变剪接导致多个转录变体。 [RefSeq 提供,2013 年 10 月]
MKNK1人源基因|MKNK1基因突变_致病性_靶点-RDDC官网
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates. Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.
Mknk1 MGI Mouse Gene Detail - MGI:894316 - MAP kinase …
View mouse Mknk1 Chr4:115696395-115736447 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
MNK1 and MNK2 Expression in the Human Dorsal Root and …
2023年4月1日 · Mitogen activated protein kinase interacting kinases (MNK) 1 and 2 are serine/threonine protein kinases that play an important role in translation of mRNAs through their phosphorylation of the RNA 5′-cap binding protein, eukaryotic translation initiation factor (eIF) 4E.
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