2025年2月12日 · Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) represents a group of inflammatory demyelinating disorders united by the presence of IgG antibodies to myelin oligodendrocyte glycoprotein (MOG).

髓鞘少突胶质细胞糖蛋白（myelin oligodendrocyte glycoprotein，MOG）是一种只在中枢神经系统（central nervous system，CNS）少突胶质细胞膜上表达的髓鞘蛋白，位于髓鞘最外层表面，在髓鞘构成中所占比例不足0.0…

2023年7月7日 · Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a novel inflammatory demyelinating disease of the central nervous system. This study aims to characterize the MRI features of MOGAD and contrast our results with the findings previously described in the literature and its close differential diagnoses.

2 天之前 · For those with low MOG antibody titers, MOGAD-MRI features improved negative predictive value, particularly for brain MRI as well, suggesting the absence of these MRI features in low titer patients is very helpful in ruling out MOGAD. Lesion resolution is also highly associated with a MOGAD diagnosis (versus entities such as MS) and should be ...

2019年9月1日 · In this review, we will briefly outline the clinical presentation of MOG-SD in adults and discuss their MRI features in detail. MOG-AD can occur in all decades of life, with a median age of onset in the early to mid-thirties, and it affects slightly more women than men (female: male ratio = 1.1:1) [5], [9], [10], [11], [12], [13].

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is the most recently defined inflammatory demyelinating disease of the central nervous system (CNS). Over the last decade, several studies have helped delineate the ...

The spectrum of Myelin Oligodendrocytes Glycoprotein (MOG) antibody disease constitutes a recently described challenging entity, referring to a relatively new spectrum of autoimmune disorders with antibodies against MOG predominantly involving the optic nerve and spinal cord.

2022年8月24日 · Serum antibodies to myelin-oligodendrocyte glycoprotein (MOG) are biomarkers of MOG-IgG-associated disorder (MOGAD), a demyelinating disease distinct from both multiple sclerosis (MS) and aquaporin-4-IgG neuromyelitis optica spectrum disorder (NMOSD).

MRI is instrumental in distinguishing neuromyelitis optica spectrum disorder (NMOSD) from multiple sclerosis (MS), but MRI features of MOG disease appear to overlap with NMOSD and MS. In this study we aim to characterize the radiological features of MOG antibody disease and compare the findings with those previously described. Methods.

3 天之前 · A brain MRI of cortical encephalitis reveals high cerebral signals in the FLAIR sequence. We observed the evolution of cortical involvement in MOG-AD. Our patient initially had unilateral cortical involvement. As the disease progressed, the other side became affected as well. There are sporadic cases of aseptic meningitis associated with MOG-Ab ...