2024年12月25日 · MT-CYB (Mitochondrially Encoded Cytochrome B) is a Protein Coding gene. Diseases associated with MT-CYB include Cardiomyopathy, Infantile Histiocytoid and Leber Hereditary Optic Neuropathy, Modifier Of .

Its gene product is a subunit of the respiratory chain protein ubiquinol–cytochrome c reductase (UQCR, complex III or cytochrome bc 1 complex), which consists of the products of one mitochondrially encoded gene, MT-CYB (mitochondrial cytochrome b), and ten nuclear genes—UQCRC1, UQCRC2, CYC1, UQCRFS1 (Rieske protein), UQCRB, "11kDa protein ...

The MT-CYB gene provides instructions for making a protein called cytochrome b. This protein plays a key role in structures called mitochondria, which convert the energy from food into a form that cells can use. Learn about this gene and related health conditions.

预测可启用金属离子结合活性。 预计参与多个过程，包括电子传输耦合质子传输；对钴胺素的反应；和对胰高血糖素的反应。 位于线粒体中。 与卵巢癌和膀胱癌有关。 [由基因组资源联盟提供，2022 年 4 月] Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including electron transport coupled proton transport; response to cobalamin; and response to glucagon. Located in mitochondrion.

Cytochrome b (MTCYB) is the only mitochondrial DNA (mtDNA) encoded subunit of respiratory Complex III (ubiquinol:ferrocytochrome c oxidoreductase, or cytochrome bc1, complex, EC 1.10.2.2).

Complex III, ubiquinone–cytochrome c oxidoreductase, is composed of 11 subunits of which only one (cytochrome b) is encoded by the mitochondrial genome. Cytochrome B (MT-CYB), along with cytochrome c1 (CYC1) and the Rieske protein (UQCRFS1) represent the catalytic center.

线粒体编码细胞色素b (Mitochondriallyencodedcytochromeb,MT-CYB)是线粒体氧化呼吸链中复合物Ⅲ的关键酶，MT-CYB参与这些带负电荷的电子颗粒的转移来驱动复合物Ⅲ产生ATP。 但MT-CYB是否在结直肠癌的发生发展中产生影响尚不清楚。 本课题利用免疫组织化学技术 (Immunohistochemistry,IHC)检测MT-CYB在CRC组织中的蛋白表达水平，以明确MT-CYB的表达与CRC患者临床病理及生存预后的相关性。 方法 本研究分为两部分，第一部分为MT-CYB单 …

2025年2月8日 · Title: Association between the single nucleotide variants of the mitochondrial cytochrome B gene (MT-CYB) and the male infertility. Liver mitochondrial DNA damage and genetic variability of Cytochrome b - a key component of the respirasome - drive the severity of fatty liver disease.

Mutations in mitochondrial DNA, particularly in MT-CYB coding for cytochrome B in complex III (CIII), have been associated with isolated hypertrophic cardiomyopathy (HCM). We hypothesized that MT-CYB mutations might play an important causal or modifying role in HCM.

2024年4月30日 · Clinical resource with information about MT-CYB, Juvenile myopathy, encephalopathy, lactic acidosis AND stroke, Leber optic atrophy, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.