2024年12月25日 · MT-TH (Mitochondrially Encoded TRNA-His (CAU/C)) is an RNA Gene, and is affiliated with the tRNA class. Diseases associated with MT-TH include Rare Mitochondrial Non-Syndromic Sensorineural Deafness and Mitochondrial Disease With Hypertrophic Cardiomyopathy.

MT-TH is a small 69 nucleotide transfer RNA (human mitochondrial map position 12138–12206) that transfers the amino acid histidine to a growing polypeptide at the ribosomal site of protein synthesis during translation. [4] Mutations in MT-TH can result in multiple mitochondrial deficiencies and associated disorders.

The MT-TH gene provides instructions for making a particular type of RNA, a molecule that is a chemical cousin of DNA. This type of RNA, called transfer RNA (tRNA), helps assemble protein building blocks known as amino acids into full-length, functioning proteins.

2023年10月10日 · Clinical resource with information about MT-TH, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

所以你拿到自己的表达矩阵后，其实简单的看看基因名字是否以 mt- 开头即可哦。 所以你会看到 seurat包 的函数： PercentageFeatureSet 可以用来计算线粒体基因含量。

2011年10月26日 · Endomyocardial biopsy demonstrated marked loss or disruption of sarcomeres and massive accumulation of mitochondria of various sizes. In the tRNA of both brothers, a G-to-A transition was found at position 12192 in the MTTH gene. The mutation was located 2 bp from the 3-prime end of the T-psi-C loop of the tRNA.

粒線體DNA （英語： mitochondrial DNA， 縮寫 作 mtDNA）是 真核細胞 中一些位於 粒線體 內的 DNA，與一般位於 細胞核 內的DNA有不同的 演化 起源，可能是源自早期 細菌。 雖然現存真核生物體中絕大多數作用於粒線體的蛋白質，是由細胞核DNA所製造，但這些基因中有一些可能是源於細菌，並於演化過程中轉移到細胞核中，稱為 核內線粒體片段 （英语：Numt）。 現今人類體內的每個 細胞 中，大約有1000到10000個粒線體，而每一個粒線體內，則大約有2到10 …

关于 MT-TH. Compound Screening Libraries 实体化合物库 Virtual Screening 虚拟筛选 Customize Your Library 定制专属化合物库 Drug Screening Service 药物筛选服务 关联疾病. 疾病名称 别名; Mitochondrial Disease With Hypertrophic Cardiomyopathy ...

SMT是表面贴装技术（Surface Mounting Technology的缩写），称为表面贴装或表面安装技术，是目前电子组装行业里最流行的一种技术和工艺。 它是一种将无引脚或短引线或球的矩阵排列封装的表面组装元器件（简称SMC/SM…

α-MT是一种口服TH抑制剂，可用于治疗嗜铬细胞瘤引起的继发性高血压、肌张力障碍和亨廷顿病等疾病 [42, 61]。α-MT能减轻α-syn突变体和PINK1突变体诱导的神经元退化[40, 58]。