Mucin-4 (MUC-4) is a mucin protein that in humans is encoded by the MUC4 gene. [3] Like other mucins, MUC-4 is a high-molecular weight glycoprotein. [4] The major constituents of mucus, …

MUC4, a high molecular weight glycoprotein that functionally contributes to PC pathogenesis, is an attractive TAA. It is not detected in the normal pancreas; however, it is overexpressed in …

2024年12月25日 · MUC4 (Mucin 4, Cell Surface Associated) is a Protein Coding gene. Diseases associated with MUC4 include Biliary Tract Cancer and Adenosquamous Carcinoma. Among …

2018年2月1日 · Mucin 4 is a cell surface associated mucin encoded by MUC4 gene and is localized to chromosome locus 3q29 (Gross et al., 1992). Mucin 4 expression has been …

MUC4, a member of transmembrane mucin family, is expressed in airway epithelial cells and body fluids like saliva, tear film, ear fluid, and breast milk. In addition to its normal expression, an …

The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These …

2021年12月9日 · MUC4 is a transmembrane mucin expressed on various epithelial surfaces, including respiratory and gastrointestinal tracts, and helps in their lubrication and...

The most highly up-regulated gene was mucin 4 (MUC4), and its protein product was confirmed to be over-expressed in periodontitis; MUC4 has a role in promoting neural invasion mediated by …

2017年9月11日 · Mucin-4 (Muc4) is a large cell surface glycoprotein, composed of a heavily O-glycosylated extracellular alpha subunit and a membrane-anchored beta subunit that normally …

2025年2月8日 · Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA …