Myb genes are part of a large gene family of transcription factors found in animals and plants. In humans, it includes Myb proto-oncogene like 1 and Myb-related protein B in addition to MYB proper.

2024年12月25日 · MYB (MYB Proto-Oncogene, Transcription Factor) is a Protein Coding gene. Diseases associated with MYB include Adenoid Cystic Carcinoma and Angiocentric Glioma. Among its related pathways are Gene expression (Transcription) and ESR-mediated signaling.

2021年2月26日 · In humans, the MYB gene family is composed of three members: MYB, MYBL1 and MYBL2, encoding the transcription factors MYB, MYBL1, and MYBL2 (also known as c-MYB, A-MYB, and B-MYB),...

Because of its role in oncogenesis, MYB is now a compelling target for therapeutic interventions in cancer research. This review summarizes its molecular functions and current therapeutic approaches aiming to inhibit its oncogenic activity. Keywords: MYB, inhibitor, AML, leukemia, adenoid cystic carcinoma, transcription, p300, gene expression. 1.

The MYB gene is a master regulator of hematopoietic system development and function and deregulated MYB expression in humans leads to a constellation of hematological and non-hematological malignancies.

1999年5月13日 · The myb gene family consists of three members, named A, B and c-myb which encode nuclear proteins that function as transcriptional transactivators.

2025年2月8日 · efg; Cmyb; c-myb; c-myb_CDS Summary This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis.