2024年12月25日 · MYO9B (Myosin IXB) is a Protein Coding gene. Diseases associated with MYO9B include Celiac Disease 4 and Celiac Disease. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and RHOC GTPase cycle.

Overview of all the structural information available in the PDB for UniProt: Q13459 (Human Unconventional myosin-IXb (MYO9B)) at the PDBe-KB

2007年10月29日 · Background & Aims: Celiac disease (CD) is associated with HLA-DQ2 and HLA-DQ8 and has been linked to genetic variants in the MYO9B gene on chromosome 19. HLA-DQ2 homozygosity is associated with complications of CD such as refractory celiac disease type II (RCD II) and enteropathy-associated T-cell lymphoma (EATL).

2023年9月25日 · Genomic comparative analysis maps a 33-bp deletion in the ALR Myosin IXb (Myo9b) gene when compared with NOD genome; meanwhile, data from knock-in models show that this ALR Myo9b allele impairs...

2023年9月26日 · 9月25日，中山大学/中南大学/华中科技大学研究人员在期刊《Nature Communications》上发表题为“Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset”的研究论文，研究结果暗示 Myo9b的改变可能导致树突状细胞功能的改变和自身免疫性糖尿病的发病。 研究背景. 01. 1型糖尿病（T1D）是一种以胰岛素分泌β细胞的严重损伤为特征的自身免疫性疾病。 它具有复杂的病 …

2024年12月10日 · Title: Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset. Mutations in MYO9B are associated with Charcot-Marie-Tooth disease type 2 neuropathies and isolated optic atrophy.

Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset. Mutations in MYO9B are associated with Charcot-Marie-Tooth disease type 2 neuropathies and isolated optic atrophy.

Myo9b is a motor–RhoGAP chimera that has been implicated in inflammatory bowel disease. Findings suggest that Myo9b is essential during both collective and individual wound-induced cell migration. It is also important for maintaining tight junction barrier integrity.

2025年2月8日 · Clinical resource with information about MYO9B, Hundreds of variants clustered in genomic loci and biological pathways affect human height., Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians., and available tests.

2020年11月15日 · Taken together, Myo9b deficiency suppresses MPE development not only by suppressing pleural cancer metastasis but also by regulating T H 1/T H 17 cell response via a TSAd-dependent pathway. This work suggests Myo9b and TSAd as novel candidates for future basic and clinical investigations of cancer.