MyoD is a 3D genome structure organizer for muscle cell identity
2022年1月11日 · We show that MyoD functions as a “genome organizer” that specifies 3D genome architecture unique to muscle cell development, and that H3K27ac is insufficient for …
Function of the myogenic regulatory factors Myf5, MyoD ... - PubMed
Discovery of the myogenic regulatory factor family of transcription factors MYF5, MYOD, Myogenin and MRF4 was a seminal step in understanding specification of the skeletal muscle …
Muscle regeneration controlled by a designated DNA dioxygenase
2021年5月25日 · Tet2 activates transcription of the key differentiation modulator Myogenin (MyoG) by actively demethylating its enhancer region. Re-expressing of MyoG in Tet2 KO …
MyoG基因结构与功能研究进展 - 百度学术
肌细胞生成素 (myogenin,MyoG)是生肌调节因子MRFs (MyoD,MyoG,Myf5和MRF4)家族的一员,它的表达具有控制成肌细胞融合的起始,促使成肌细胞的增殖作用,使单核成肌细胞转变成为多核 …
肌分化因子MyoD的研究进展 - 百度学术
肌分化因子MyoD (亦称MyoDI),是生肌调节因子 (myogenic regulatory factors,MRFs)家族四成员 (MyoD,MRF5,myoG,MRF4)之一,1987年首次被克隆.MyoD基因不仅可促使静止期的肌卫星细 …
Myogenin is required for assembly of the transcription machinery …
2021年1月19日 · We show here that MYOG is required for the recruitment of TBP and RNAPII to muscle gene promoters, indicating that MYOG is essential in assembling the transcription …
Function of the myogenic regulatory factors Myf5, MyoD, Myogenin …
2017年12月1日 · Discovery of the myogenic regulatory factor family of transcription factors MYF5, MYOD, Myogenin and MRF4 was a seminal step in understanding specification of the skeletal …
生肌调节因子及肌生成调控因素研究进展 - 百度学术
生肌调节因子（myogenic regulatory factors,MRFs）是调控肌肉生成的重要基因,家族中包括MyoD、MyoG、Myf5和Myf6。 MyoD能把多种类型细胞转化为成肌细胞,在肌肉特异基因转录 …
在骨骼肌分化过程中，肌生成素是在肌肉基因上组装转录机制所必 …
Skeletal muscle gene expression is governed by the myogenic regulatory family (MRF) which includes MyoD (MYOD1) and myogenin (MYOG). MYOD1 and MYOG are known to regulate …
The Myogenic Regulatory Factors, Determinants of Muscle …
The Myogenic Regulatory Factors (MRFs) Myf5, MyoD, myogenin and MRF4 are members of the basic helix-loop-helix family of transcription factors that control the determination and …