2024年12月25日 · MYOF (Myoferlin) is a Protein Coding gene. Diseases associated with MYOF include Angioedema, Hereditary, 7 and Hereditary Angioedema With Normal C1inh Not Related To F12 Or Plg Variant. Among its related pathways are Nuclear receptors meta-pathway and Signaling events mediated by VEGFR1 and VEGFR2.

Myoferlin is a protein that in humans is encoded by the MYOF gene. [5] [6] [7] [8] Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar

2025年2月9日 · The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane ...

Myoferlin (MYOF), initially identified in muscle cells, is a member of the Ferlin family involved in membrane fusion, membrane repair, and membrane trafficking. Dysfunction of this protein is associated with muscular dysfunction. Recently, a growing body of studies have identified MYOF as an oncogenic protein.

2025年2月9日 · Myoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer. MYOF regulates cell adhesions and cell-substrate adhesion strength and may account for the high degree of motility in invasive breast cancer cells.

2025年1月4日 · The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane ...

The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane ...

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes.

肌营养不良蛋白，一种与质膜相关的蛋白质，可引起肌肉无力，影响近端和远端肌肉。 这个基因编码的蛋白质是一种II型膜蛋白，在结构上与肌营养不良蛋白相似。 它是ferlin家族的一员，并与质膜和核膜结合。 该蛋白质含有C2结构域，在钙介导的膜融合事件中发挥作用，提示它可能参与膜的再生和修复。 已发现该基因有两个转录变异体，编码不同的异构体。 还检测到了其他可能的变异体，但其全长性质尚未确定。 [RefSeq，2008年12月提供] 该模块正在开发中，请耐心等待我 …

2022年7月31日 · The protein encoded by this gene, "myoferlin," is a type II membrane protein structurally similar to dysferlin (dysferlin, also known as dystrophy-associated Fer-1-like protein; is associated with skeletal muscle repair). It is a member of the Ferlin family and associates with both plasma and nuclear membranes.