2024年12月25日 · MYRF (Myelin Regulatory Factor) is a Protein Coding gene. Diseases associated with MYRF include Cardiac-Urogenital Syndrome and …

MyRF is a transcription factor that promotes the expression of many genes important in the production of myelin. [7] It is therefore of critical importance in the development and …

2025年1月4日 · De novo variants in Myelin regulatory factor (MYRF) as candidates of a new syndrome of cardiac and urogenital anomalies. Autosomal dominant nanophthalmos and high …

该基因编码中枢神经系统髓鞘形成所需的转录因子，并可能调节少突胶质细胞分化。 它被认为通过增加影响髓磷脂生成的基因表达来发挥作用，但也可能直接促进髓磷脂基因表达。 小鼠模型 …

The Myelin Regulator Factor (MYRF) is a master regulator governing myelin formation and maintenance in the central nervous system. The conservation of MYRF across metazoans and …

In particular, the oligodendrocyte transcription factor myelin regulatory factor (MYRF) is essential for myelination during development, but its role during remyelination and expression in MS …

2020年1月21日 · Myrf is a membrane-bound transcription factor that plays a key role in various biological processes. The Intramolecular Chaperone Auto-processing (ICA) domain of Myrf …

2021年4月17日 · The myelin regulatory factor gene (MYRF) encodes a protein evolutionarily conserved from invertebrates to vertebrates, representing a novel type of membrane-bound …

2025年1月4日 · Title: Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis. Functional mechanism and pathogenic potential of MYRF ICA domain …

Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including central nervous system myelin maintenance; …