The nucleus accumbens (NAc or NAcc; also known as the accumbens nucleus, or formerly as the nucleus accumbens septi, Latin for 'nucleus adjacent to the septum') is a region in the basal forebrain rostral to the preoptic area of the hypothalamus. [1] The nucleus accumbens and the olfactory tubercle collectively form the ventral striatum.

2024年9月30日 · While NAC is undoubtedly a promising tool for brain health, it’s important to remember that no supplement exists in a vacuum. To truly maximize NAC’s potential benefits, it’s crucial to consider it as part of a broader, holistic approach to brain health.

NAC is a glutathione precursor and shows antioxidant and anti-inflammatory activities. In addition to the uses quoted in the literature, NAC may be considered helpful in therapies to counteract neurodegenerative and mental health diseases.

2023年10月30日 · Main nuclei of the basal ganglia and surrounding structures (20 structures). Synonyms: NAc, NAcc , show more... The nucleus accumbens is part of a large group of subcortical nuclei collectively called the basal ganglia (basal nuclei). It lies in the rostral cerebral hemisphere, in the ventral forebrain.

2019年10月17日 · Studies have investigated the effectiveness of NAC both as a stand-alone and adjunctive treatment of depressed mood, bipolar disorder, schizophrenia, and trichotillomania, as well as nicotine,...

2024年8月6日 · Neural processing of rewarding stimuli involves several distinct regions, including the nucleus accumbens (NAc). The majority of NAc neurons are GABAergic projection neurons known as medium...

2024年10月1日 · N-acetyl-L-cysteine (NAC) restores cellular glutathione, a key antioxidant that drops with age. Studies suggest NAC reduces brain aging and the risk for neurodegenerative conditions.

2022年1月31日 · Using a three-chamber vicarious social defeat stress (3C-VSDS) model in mice, we here show that chronic emotional stress (CES) induces anxiety-like behavior and transient social interaction...

2014年1月13日 · Several experimental studies have found that NAC plays a neuroprotective role by repairing traumatic brain injury (TBI)-induced mitochondrial dysfunction and by increasing the reduced antioxidant enzyme (Xiong et al. 1999; Hicdonmez et al. 2006; Yi et al. 2006).

N-acetylcysteine (NAC), widely known as an antidote to acetaminophen overdose, is now emerging as treatment of vascular and nonvascular neurological disorders. NAC as a precursor to the antioxidant glutathione modulates glutamatergic, neurotrophic, and inflammatory pathways.