2020年3月1日 · A major diagnostic application of 18 F-NaF PET scan that has been explored is its use in the detection of osseous lesions of metastatic cancers such as breast, prostate, and lung cancers.

Fluorine 18-Fluorodeoxyglucose positron emission tomography/computerized tomography (18F-FDG PET/CT) is now used as a useful imaging tool for staging, restaging and evaluation of therapy response for most cancers.

2020年4月3日 · Fluorine-18-labeled sodium fluoride (also known as 18F-NaF or sodium fluoride) is a PET radiotracer used primarily for skeletal imaging. Fluorine-18-labeled sodium fluoride is an ionic compound comprised of a single sodium atom …

2010年11月1日 · 18 F is a diagnostic molecular imaging agent used for identification of new bone formation. 18 F, administered as intravenous Na 18 F, was approved by the U.S. Food and Drug Administration in 1972 but has been listed as a discontinued drug since 1984.

2021年6月1日 · 18F-NaF PET/CT is indicated for diagnostic imaging of bone to define altered osteogenic areas of activity. It provides high-resolution, high-contrast images of the skeletal tissue and has higher sensitivity, specificity, and accuracy than conventional nuclear bone scintigraphy.

Despite the historical legacy and widespread current clinical practice that employs 99m Tc-based bone scintigraphy, the use of positron emission tomography (PET) with 18 F-sodium fluoride (18 F-NaF) is increasing. 18 F-NaF was introduced in 1962 and approved for clinical use by the U.S. Food and Drug Administration in 1972 (2, 3).

2016年5月16日 · We aim to evaluate 18 F-NaF uptake by facet joints with hybrid PET-CT technique. Specifically, we evaluate NaF uptake in the facet joints of the lower lumbar spine, and correlate with the morphologic grade of facet arthropathy on CT. 30 consecutive patients who underwent standard vertex to toes NaF PET-CT for re-staging of primary neoplastic ...

18F is a diagnostic molecular imaging agent used for identification of new bone formation. 18F, administered as intravenous Na18F, was approved by the U.S. Food and Drug Administration in 1972 but has been listed as a dis-continued drug since 1984.

2018年4月27日 · NaF PET/CT hybrid fusion imaging is extremely useful in identifying potential causes of pain in patients with malignancies that have an affinity for skeletal metastases. This technique can help detect bone metastases, in problem solving, and to …

Radiologists have used 18-F Sodium Fluoride (NaF-18) to view abnormal activity in bone since the U.S. Food and Drug Administration first approved it in 1972. NaF-18 bone scans are more specific and sensitive than conventional bone scans, providing high contrast images on PET/CT scans within about an hour of injection.