2018年6月11日 · In the present study, a lentivirus was used to deliver shRNA targeting NF-κB1 into mouse RCC (Renca) cells. It was determined that the knockdown of the NF-κB1 gene led …

2008年5月1日 · Quantitative PCR analysis demonstrated greater than 80% knockdown of NfkB1 in both shRNA cell lines relative to non-transduced or scrambled shRNA control cell lines. …

2018年6月11日 · In the present study, a lentivirus was used to deliver shRNA targeting NF-κB1 into mouse RCC (Renca) cells. It was determined that the knockdown of the NF-κB1 gene led …

2023年9月30日 · A novel heterogeneous NFKB1 mutation (c.889 G > T) was identified (Fig. S1B) and subsequently confirmed by Sanger sequencing (Fig. S1C). This mutation was found in the …

2017年4月3日 · In this study, we examine the relationships between signaling of the two NF-κB subunits p100 and p105, DLBCL phenotypes and the coding genome by integrating gene …

2017年4月5日 · We observed that 72 h after shRNA transduction, expression of CD47 transcript and protein (measured by flow cytometry) was significantly reduced by NFKB1 (Fig. 3b,c) and …

Here we discuss recent results that reveal that the nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1) (p105/p50) subunit is an important regulator of NF-κB activity in …

Without radiation, cell counting kit-8 (CCK-8) assays showed that knockdown of NFKB1 significantly increased the rate of cell growth and colony formation, as compared with the …

2017年7月20日 · Application of novel gene expression classifiers identified two new DLBCL categories characterized by selective p100 (NF-κB2) and p105 (NF-κB1) signaling. …

We found that the administration of NIK-SMI1 strongly inhibited the RANKL-stimulated non-canonical NF-κB signaling as demonstrated by decreased nuclear p52 expression and activity. …

Activation of C/EBPα-ER results in rapid induction of nfkb1 mRNA that is not abrogated by cycloheximide, consistent with direct transcriptional induction. C/EBPα activation of the nfkb1 …

2017年4月5日 · Thus, NFKB1 binding to CD47 E5 works as a switch for the regulation of CD47 expression. To turn off this regulatory switch, we performed an shRNA knockdown to inhibit …

Intriguingly, CHI3L1 binds to actinin alpha 4 (ACTN4) and NFKB1, and enhances the NF-κB signaling pathway by promoting the NF-κB subunit nuclear translocation in glioma cells. …

2023年4月24日 · Here we show that, in VHL-deficient renal tumours, PBRM1 deficiency results in ectopic PBAF complexes that localize to de novo genomic loci, activating the pro-tumourigenic …

2021年7月9日 · Here we describe the design and use of short hairpin RNA (ShRNA) and lentiviral vectors as an efficient technique for silencing NF-kappaB (NF-κB) pathway in cultured cells. …

2024年12月25日 · NFKB1 (Nuclear Factor Kappa B Subunit 1) is a Protein Coding gene. Diseases associated with NFKB1 include Immunodeficiency, Common Variable, 12, With …

Supplier Page from OriGene Technologies for NFKB1 Human shRNA Plasmid Kit (Locus ID 4790) Description NFKB1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector

Use shRNA set against Human NFKB1 (NM_001165412.1) for functional genomics research and drug discovery study.

Nfkb1 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

Ready-to-use AAV expressing shRNA for silencing of Human NFKB1 (nuclear factor kappa B subunit 1). Available with optional GFP reporter or cell-specific promoter.