The NIH Intramural Sequencing Center (NISC), established in 1997, is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence. In addition to providing investigators at the NIH access to well established, high-throughput DNA sequencing, NISC works closely with NIH collaborators to explore the use and ...

2023年3月7日 · The NIH Intramural Sequencing Center (NISC), established in 1997, is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence. In addition to providing investigators at the National Institutes of Health (NIH) access to well established, high-throughput DNA sequencing, NISC works closely with NIH ...

2021年7月12日 · 其实就是所谓的ZISC，全称zero instruction set computer，或者无指令计算（NISC，no instruction set computing）。 除此之外，仅含1条指令的话就是OISC，one instruction set computer。

Base calling is done in real time making sequence data available right from the start of the run. DNA read accuracy, including modified base detection is currently >99%. The primary uses of this technology to date at NISC have taken advantage of the ultra-long reads to detect large structural variants and create de novo genome assemblies.

NHGRI has selected James Thomas, Ph.D., as the new director of the NIH Intramural Sequencing Center (NISC), to will oversee the importation and use of DNA sequencing technologies, protocols and analyses, ensuring that NIH investigators have access to cutting-edge DNA sequencing methods and specialized genomics protocols to meet their research ...

We aim to provide the highest quality sequencing data possible to the NIH community. We meet with every investigator interested in starting a sequencing project to discuss the best sequencing approach for their research needs. Please note that our sequencing service is restricted to intramural investigators at the NIH.

NISC's role within NHGRI, and more broadly across NIH, aims to advance genome sequencing and its many applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to bring genomic sequence to biology and medicine. We accomplish this by meeting with each NIH investigator to discuss the details of ...

companies across the nation. NISC is an industry leader providing advanced, integrated IT solutions for consumer and subscriber billing, accounting, engineering & operations, as well as many oth.

In this report we try to answer both of these questions and argue that the No-instruction-set computer (NISC) is a single, necessary and sufficient processor component for design of any digital system. In order to introduce the concept of NISC processor and its benefits, we will first compare NISC features to those of CISC and RISC processors.

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