Full article: The naked mole-rat as an animal model in biomedical ...
2015年8月11日 · The naked mole-rat (NMR) (Heterocephalus glaber) is a subterranean mammal, which has recently gained interest from scientists across a variety of research fields. Unlike …
Naked Mole Rat Cells Have a Stable Epigenome that Resists …
2017年11月14日 · Naked mole rat (NMR) is a valuable model for aging and cancer research due to its exceptional longevity and cancer resistance. We observed that the reprogramming …
Naked mole rat TRF1 safeguards glycolytic capacity and telomere ...
The naked mole rat (NMR), a long-lived and cancer-resistant rodent, is highly resistant to hypoxia. Here, using robust cellular models wherein the mouse telomeric protein TRF1 is substituted by …
Naked mole-rat very-high-molecular-mass hyaluronan exhibits …
2020年5月12日 · Naked mole-rat (NMR), the longest-living rodent, produces very-high-molecular-mass hyaluronan (vHMM-HA), compared to other mammalian species. However, it is unclear if …
Naked mole rat cells display more efficient excision repair than …
Naked mole rat (NMR) is the long-lived and tumor-resistant rodent. NMRs possess multiple adaptations that may contribute to longevity and cancer-resistance. However, whether NMRs …
Naked Mole Rat Induced Pluripotent Stem Cells and Their …
2017年11月14日 · The naked mole rat (NMR; Heterocephalus glaber) (Figure 1 A, top) is an emerging model organism for studies on aging and cancer. While NMRs and mice have a …
Epigenetic aging of the demographically non-aging naked mole-rat …
2022年1月17日 · The naked mole-rat (NMR) is an exceptionally long-lived rodent that shows no increase of mortality with age, defining it as a demographically non-aging mammal.
An updated reference genome sequence and annotation reveals
2024年11月26日 · The naked mole-rat (NMR; Heterocephalus glaber) is a eusocial subterranean rodent with a highly unusual set of physiological traits that has attracted great interest amongst …
Probing the unfolded protein response in long-lived naked mole-rats
2020年9月9日 · The long-living naked mole-rat (NMR) shows negligible senescence and resistance to age-associated diseases. Recent evidence, based on protein-level assays, …
Naked mole-rats: at the heart of it - ScienceDirect
2024年10月1日 · Faulkes et al. recently showed that naked mole-rats (NMRs) have a very distinctive cardiac gene expression profile among other African mole-rats, as well as metabolic …